ArticleHippocampus2019
The hippocampus is necessary for the consolidation of a task that does not require the hippocampus for initial learning.
Article in Hippocampus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sleep deprivation and memory: Meta-analytic reviews of studies on sleep deprivation before and after learning.Psychological bulletin · 2021Pooled it
- Replay of procedural memory is independent of the hippocampus.Nature neuroscience · 2026Article
- Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents.Brain and behavior · 2026Review
- Comparative effects of diazepam administration and chronic sleep deprivation on cognitive function and biochemical markers in rats.Scientific reports · 2026Article
- Virtual Morris Water Task: Procedures and Protocols for the Assessment of Spatial Navigation and Memory.Current protocols · 2026Article
- Article
- Hippocampal Ripples during Offline Periods Predict Human Motor Sequence Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Hippocampal functional connectivity changes associated with active and lecture-based physics learning.bioRxiv : the preprint server for biology · 2025Article
- Uncovering the Role of the Human Hippocampus in Procedural Motor Learning: Insights from Implicit Sensorimotor Adaptation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Disrupted flexible use of context-dependent relational memory in adults following moderate-severe traumatic brain injury.Neuropsychologia · 2025Article
- Hippocampal ripples predict motor learning during brief rest breaks in humans.Nature communications · 2025Article
- The human medial temporal lobe represents memory items in their ordinal position in both declarative and motor memory domains.PLoS biology · 2025Article
- Continuous Diffusion-Detected Neuroplasticity during Motor Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Does sleep benefit source memory? Investigating 12-h retention intervals with a multinomial modeling approach.Memory & cognition · 2025Article
- Multi-region processing during sleep for memory and cognition.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025Review
- Hippocampus supports long-term maintenance of language representations: Evidence of impaired collocation knowledge in amnesia.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Correlating clinical course with baseline subcortical shape in provisional tic disorder.CNS spectrums · 2024Article
- Article
- The Role of the Hippocampus in Consolidating Motor Learning during Wakefulness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- The Hippocampus Represents Information about Movements in Their Temporal Position in a Learned Motor Sequence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
During sleep, the hippocampus plays an active role in consolidating memories that depend on it for initial encoding. There are hints in the literature that the hippocampus may have a broader influence, contributing to the consolidation of memories that may not initially require the area. We tested this possibility by evaluating learning and consolidation of the motor sequence task (MST) in hippocampal amnesics and demographically matched control participants. While the groups showed similar initial learning, only controls exhibited evidence of overnight consolidation. These results demonstrate that the hippocampus can be required for normal consolidation of a task without being required for its acquisition, suggesting that the area plays a broader role in coordinating memory consolidation than has previously been assumed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.