ArticleLasers in surgery and medicine2019
Antimicrobial Blue Light Inactivation of Neisseria gonorrhoeae: Roles of Wavelength, Endogenous Photosensitizer, Oxygen, and Reactive Oxygen Species.
Article in Lasers in surgery and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The Use of Blue Light as an Antimicrobial Treatment Against Staphylococcus aureus: A Systematic Review.Lasers in surgery and medicine · 2026Pooled it
- Violet photobiomodulation: biological effects and health implications.Lasers in medical science · 2025Pooled it
- The potential role of violet-blue light to preventing hospital acquired infections: a systematic review.Frontiers in public health · 2024Pooled it
- Illuminating the mechanism: gene expression responses to antimicrobial photodynamic therapy.BMC genomics · 2026Review
- Parameter optimization and mechanism of action of Light‑Emitting Diode phototherapy in a rat model of bacterial vaginosis.Frontiers in cellular and infection microbiology · 2026Article
- Natural Biomolecules and Light: Antimicrobial Photodynamic Strategies in the Fight Against Antibiotic Resistance.International journal of molecular sciences · 2025Review
- The combined 410nm and infrared light effectively suppresses bacterial survival under realistic conditions.Frontiers in cellular and infection microbiology · 2025Article
- Mimicking the Effects of Antimicrobial Blue Light: Exploring Single Stressors and Their Impact on Microbial Growth.Antioxidants (Basel, Switzerland) · 2024Article
- Antimicrobial blue light inactivation of Pseudomonas aeruginosa: Unraveling the multifaceted impact of wavelength, growth stage, and medium composition.Journal of photochemistry and photobiology. B, Biology · 2024Article
- Antimicrobial Resistance: Is There a 'Light' at the End of the Tunnel?Antibiotics (Basel, Switzerland) · 2023Review
- An Approach to Improve Energy Efficiency during Antimicrobial Blue Light Inactivation: Application of Pulse-Width Modulation Dimming to Balance Irradiance and Irradiation Time.Antibiotics (Basel, Switzerland) · 2023Article
- Safer school with near-UV technology: novel applications for environmental hygiene.Journal of environmental health science & engineering · 2023Article
- Effects of Light on Growth and Metabolism ofMicroorganisms · 2022Article
- The microbicidal potential of visible blue light in clinical medicine and public health.Frontiers in medicine · 2022Review
- Antimicrobial Blue Light for Prevention and Treatment of Highly InvasiveFrontiers in microbiology · 2022Article
- Pulsed blue light inactivates two strains of human coronavirus.Journal of photochemistry and photobiology. B, Biology · 2021Article
- Quinine Improves the Fungicidal Effects of Antimicrobial Blue Light: Implications for the Treatment of Cutaneous Candidiasis.Lasers in surgery and medicine · 2020Article
- Photoinactivation of Moraxella catarrhalis Using 405-nm Blue Light: Implications for the Treatment of Otitis Media.Photochemistry and photobiology · 2020Article
- Article
- Antimicrobial Effect of Visible Light-Photoinactivation ofAntibiotics (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectivesThe aim of this study was to investigate the efficacy, safety, and mechanism of action of antimicrobial blue light (aBL) for the inactivation of Neisseria gonorrhoeae, the etiological agent of gonorrhea. STUDY DESIGN/MATERIALS AND
methodsThe susceptibilities of N. gonorrhoeae (ATCC 700825) in planktonic suspensions to aBL at 405- and 470-nm wavelengths were compared. The roles of oxygen in the anti-gonococcal activity of aBL were studied by examining the effects of hypoxic condition (blowing N
resultsAbout 3.12-log
conclusionsaBL at 405-nm wavelength is more effective than 470-nm wavelength in inactivating N. gonorrhoeae while sparing the vaginal epithelial cells. Reactive oxygen species generated from the photochemical reactions between aBL and endogenous photosensitizers play a vital role in the anti-gonococcal activity of 405-nm aBL. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.