Evidence map›Paper›PMID 31157564›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Protein phosphatase 1α interacts with a novel ciliary targeting sequence of polycystin-1 and regulates polycystin-1 trafficking.

Chong Luo, Maoqing Wu, Xuefeng Su, Fangyan Yu, David L Brautigan, Jianghua Chen, Jing Zhou

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. The GPCR properties of polycystin-1- A new paradigm.Frontiers in molecular biosciences · 2022
    Review
  4. Comparison of Ciliary Targeting of Two Rhodopsin-Like GPCRs: Role of C-Terminal Localization Sequences in Relation to Cilium Type.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. ARF family GTPases with links to cilia.American journal of physiology. Cell physiology · 2020
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Chong LuoKidney Disease Center, The First Affiliated Hospital-College of Medicine-National Key Clinical Department of Kidney Diseases, Institute of Nephrology, Zhejiang University, Hangzhou, China.
Maoqing WuHarvard Center for Polycystic Kidney Disease Research-Renal Division, Department of Medicine, Brigham and Women's Hospital-Harvard Medical School, Boston, Massachusetts, USA.
Xuefeng SuHarvard Center for Polycystic Kidney Disease Research-Renal Division, Department of Medicine, Brigham and Women's Hospital-Harvard Medical School, Boston, Massachusetts, USA.
Fangyan YuHarvard Center for Polycystic Kidney Disease Research-Renal Division, Department of Medicine, Brigham and Women's Hospital-Harvard Medical School, Boston, Massachusetts, USA.
David L BrautiganCenter for Cell Signaling, Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Jianghua ChenKidney Disease Center, The First Affiliated Hospital-College of Medicine-National Key Clinical Department of Kidney Diseases, Institute of Nephrology, Zhejiang University, Hangzhou, China.
Jing ZhouHarvard Center for Polycystic Kidney Disease Research-Renal Division, Department of Medicine, Brigham and Women's Hospital-Harvard Medical School, Boston, Massachusetts, USA.
Brigham and Women's Hospital · USZhejiang University · CNHarvard University · USUniversity of Virginia · US

Funding

Mouse model of polycystic kidney diseaseR37DK051050 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHOU, JING · 2005 to 2014
$4.2M
Cell biology of autosomal dominant polycystic kidney diseaseR01DK099532 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHOU, JING · 2014 to 2016
$796k
NIDDK NIH HHS R01 DK099532NIDDK NIH HHS R37 DK051050
6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disorder causing renal failure. Mutations of polycystic kidney disease 1 (

Indexed as

AlanineAmino Acid SequenceAnimalsCell LineMiceMice, KnockoutMutagenesisProtein Phosphatase 1Protein TransportTRPP Cation ChannelsAlanineProtein Phosphatase 1TRPP Cation ChannelsCTSPP1primary cilium

Identifiers

PMID31157564
PMCPMC6704455
OpenAlexW2948866751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.