Evidence map›Paper›PMID 31157540›Full record

ArticleBiomarkers in medicine2019

Charcot-Leyden crystal protein/galectin-10 is a surrogate biomarker of eosinophilic airway inflammation in asthma.

Sharmilee M Nyenhuis, Preeth Alumkal, Jian Du, Brian T Maybruck, Mark Vinicky, Steven J Ackerman

Open access · greenAbstract read
In one paragraph

Article in Biomarkers in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sharmilee M NyenhuisDepartment of Medicine, University of Illinois at Chicago, IL 60612, USA.
Preeth AlumkalDepartment of Biochemistry & Molecular Genetics, University of Illinois at Chicago, IL 60612, USA.
Jian DuDepartment of Biochemistry & Molecular Genetics, University of Illinois at Chicago, IL 60612, USA.
Brian T MaybruckDepartment of Biochemistry & Molecular Genetics, University of Illinois at Chicago, IL 60612, USA.
Mark VinickyDepartment of Medicine, University of Illinois at Chicago, IL 60612, USA.
Steven J AckermanDepartment of Medicine, University of Illinois at Chicago, IL 60612, USA.
University of Illinois Chicago · US

Funding

Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
Pulmonary and Critical Care Post-Doctoral Research Training ProgramT32HL082547 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FINN, PATRICIA W · 2007 to 2017
$2.7M
Center for Clinical and Translational ScienceKL2RR029878 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TOBACMAN, LARRY S · 2009 to 2011
$988k
NCATS NIH HHS UL1 TR002003NCRR NIH HHS KL2 RR029878NHLBI NIH HHS T32 HL082547
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAsthmaBiomarkersCase-Control StudiesDNA-Binding ProteinsEnzyme-Linked Immunosorbent AssayEosinophiliaEosinophilsFeasibility StudiesFemaleGalectinsGlycoproteinsHumansInflammationLysophospholipaseMaleBiomarkersDENND4A protein, humanDNA-Binding Proteinsgalectin 10, humanGalectinsGlycoproteinslysolecithin acylhydrolaseLysophospholipaseasthmabiomarkereosinophilsputum

Identifiers

PMID31157540
PMCPMC6630493
OpenAlexW2948752241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.