Evidence map›Paper›PMID 31157223›Full record

ReviewFrontiers in cell and developmental biology2019

Rewiring the Epigenetic Networks in

Anthony K N Chan, Chun-Wei Chen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 86 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Anthony K N ChanDepartment of Systems Biology, Beckman Research Institute of City of Hope, Duarte, CA, United States.
Chun-Wei ChenDepartment of Systems Biology, Beckman Research Institute of City of Hope, Duarte, CA, United States.
Beckman Research InstituteCity of Hope · US

Funding

Combinational Targeting the Feed-forward Epigenetic Circuitry in Mixed Lineage LeukemiaR37CA233691 · NCI · MAYO CLINIC ROCHESTER · PI CHEN, CHUN-WEI DAVID · 2019 to 2025
$2.8M
Role of BAZ2A in MLL-r leukemia and therapeutic responseR01CA236626 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, CHUN-WEI DAVID · 2019 to 2023
$2.2M
Epigenetic mechanisms for oncogene silencing in MLL-rearranged leukemiaR00CA197498 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, CHUN-WEI DAVID · 2017 to 2019
$747k
Epigenetic mechanisms for oncogene silencing in MLL-rearranged leukemiaK99CA197498 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CHEN, CHUN-WEI DAVID · 2016 to 2017
$308k
NCI NIH HHS K99 CA197498NCI NIH HHS R00 CA197498NCI NIH HHS R01 CA236626NCI NIH HHS R37 CA233691
6 · The paper itself

Abstract

Leukemias driven by chromosomal translocation of the mixed-lineage leukemia gene (

Indexed as

chromatinepigeneticsleukemiasMLLMLL-rearranged

Identifiers

PMID31157223
PMCPMC6529847
OpenAlexW2946413289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.