Evidence map›Paper›PMID 31157200›Full record

ArticleFrontiers in chemistry2019

Supramolecular Aptamers on Graphene Oxide for Efficient Inhibition of Thrombin Activity.

Ting-Xuan Lin, Pei-Xin Lai, Ju-Yi Mao, Han-Wei Chu, Binesh Unnikrishnan, Anisha Anand, Chih-Ching Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ting-Xuan LinDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Pei-Xin LaiDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Ju-Yi MaoDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Han-Wei ChuDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Binesh UnnikrishnanDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Anisha AnandDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Chih-Ching HuangDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
National Taiwan Ocean University · TWAcademia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene oxide (GO), a two-dimensional material with a high aspect ratio and polar functional groups, can physically adsorb single-strand DNA through different types of interactions, such as hydrogen bonding and π-π stacking, making it an attractive nanocarrier for nucleic acids. In this work, we demonstrate a strategy to target exosites I and II of thrombin simultaneously by using programmed hybrid-aptamers for enhanced anticoagulation efficiency and stability. The targeting ligand is denoted as Supra-TBA

Indexed as

anticoagulationaptamergraphene oxideself-assemblythrombin

Identifiers

PMID31157200
PMCPMC6532589
OpenAlexW2945811189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.