ArticleGlobal spine journal2019
Primary Bone Tumor of the Spine-An Evolving Field: What a General Spine Surgeon Should Know.
Article in Global spine journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Carbon fiber-reinforced polyetheretherketone implants versus titanium implants for spinal tumors: a systematic review and meta-analysis.Journal of neuro-oncology · 2026Pooled it
- Unveiling Primary Bone Tumors of the Spine: A Review of Essential Imaging Clues.Diagnostics (Basel, Switzerland) · 2025Review
- Disparities in patient enrollment of spinal oncology clinical trials.Neuro-oncology practice · 2025Article
- Article
- Primary Osseous Malignancies of the Spine.Diagnostics (Basel, Switzerland) · 2023Review
- Vertebral Primary Bone Lesions: Review of Management Options.Current oncology (Toronto, Ont.) · 2023Review
- Article
- Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience.Diagnostics (Basel, Switzerland) · 2022Article
- 3D-Printed Patient-Customized Artificial Vertebral Body for Spinal Reconstruction after TotalInternational journal of bioprinting · 2022Article
- Surgical Management of Skull Base and Spine Chordomas.Current treatment options in oncology · 2021Review
- Assessing the Mechanical Weakness of Vertebrae Affected by Primary Tumors: A Feasibility Study.Materials (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designA narrative review of the literature.
objectiveThis article reviews the general principles of treatment and investigation for primary bone tumors of the spine. Furthermore, it explores the emerging alternatives.
methodsA review was performed using Medline, Embase, and Cochrane databases.
resultsPrimary bone tumors of the spine are rare entities that general spine surgeons may encounter only a few times in their career. The treatment algorithm of these complex tumors is filled with nuances and is evolving constantly. For these reasons, patients should be referred to experienced tertiary or quaternary centers who can offer a comprehensive multidisciplinary approach. For most malignant spinal bone tumors, surgery remains the cornerstone of treatment. Respecting oncologic principles has been associated with improved survival and decreased local recurrence in multiple settings. However, even in experienced centers, these surgeries carry a significant risk of adverse events and possible long-term neurologic impairment. The associated morbidity of these procedures and the challenges of local recurrence have encouraged professionals caring for these patients to explore alternatives or adjuncts to surgical treatment.
conclusionsOver the past few years, several advances have occurred in medical oncology, radiation oncology and interventional radiology, changing the treatment paradigm for some tumors. Other advances still need to be refined before being applied in a clinical setting.
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Registered trials
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