ArticleEuropean journal of hospital pharmacy : science and practice2018
Analysis of self-reported adverse reactions to efavirenz and drug interactions in a population with HIV in Mexico.
Article in European journal of hospital pharmacy : science and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Assessment of factors associated with potential drug-drug interactions in patients with tuberculosis and HIV/AIDS.Revista da Sociedade Brasileira de Medicina Tropical · 2021Article
- Therapeutic activities of naringenin on efavirenz-induced sleep-like disorder in the midbrain of white albino mice.Iranian journal of basic medical sciences · 2020Article
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Authors and funding
6 authors.
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Abstract
objectiveTo analyse the most frequent self-reported adverse reactions (ARs), the durability and the causes of antiretrovirals (ARVs) regimens change, concomitant treatments and drug interactions related to the use of ARVs in a group of people living with HIV in Cuernavaca, Morelos, Mexico. MATERIALS AND
methodsCross-sectional study conducted in a clinic specialising in HIV 'CAPASITS-Cuernavaca' in Mexico from February to June 2015. People who wanted to participate were given a questionnaire on demographic characteristics, adherence, concomitant treatments and ARs. To understand the clinical variables, the clinical records were reviewed. Quantitative variables were compared using Student's t-test for normal data and the Mann-Whitney U test for non-normal data. For comparisons between categorical variables, the χ
resultsA total of 96 people participated, and 218 ARs (mean= 2.3±1.9) were found. The most frequently encountered ARs were dizziness (53.1%), insomnia (21.9%) and lucid dreams (17.7%). Twenty-three people (24%) were polymedicated, and 18 potential interactions were detected in 12 people.
conclusionsThe results suggest that a thorough analysis of the possible drug interactions should be performed for polymedicated people on ARV treatment and that a protocol should be designed for the monitoring and management of AR to ensure a good adherence to ARV treatment.
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