ArticleEuropean journal of hospital pharmacy : science and practice2018
Impact of a pharmaceutical care programme for patients with chronic disease initiated at the emergency department on drug-related negative outcomes: a randomised controlled trial.
Article in European journal of hospital pharmacy : science and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02368548 (Randomized Clinical Trial of a Pharmaceutical Care Program in Chronic Patients Users of an Emergency Department), which is not on this map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Clinical Trial of a Pharmaceutical Care Program in Chronic Patients Users of an Emergency Department
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Medication review in hospitalised patients to reduce morbidity and mortality.The Cochrane database of systematic reviews · 2023Pooled it
- Effectiveness of Hospital Pharmacist Interventions for COPD Patients: A Systematic Literature Review and Logic Model.International journal of chronic obstructive pulmonary disease · 2022Pooled it
- Reducing medication errors for adults in hospital settings.The Cochrane database of systematic reviews · 2021Pooled it
- Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other long-term condition: a mixed methods review.The Cochrane database of systematic reviews · 2021Pooled it
- Clinical and economic outcomes of hospital pharmaceutical care: a systematic review and meta-analysis.BMC health services research · 2020Pooled it
- Credentialed pharmacist-led home medicines reviews targeting treatable traits and their impact on health outcomes in people with chronic obstructive pulmonary disease: a pre- and post-intervention study.International journal of clinical pharmacy · 2025Trial
- The effects of a pharmacist-led medication review in a nursing home: A randomized controlled trial.Medicine · 2021Trial
- Emergency Department Reconsultations After a Secondary Prevention Bundle for Medication-Related Problems: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Healthcare risk stratification model for emergency departments based on drugs, income and comorbidities: the DICER-score.BMC emergency medicine · 2024Article
- Pharmacist Intervention in Portuguese Older Adult Care.Healthcare (Basel, Switzerland) · 2022Review
- Clinical practice and teaching of pharmaceutical care procedures for obstetric diseases.European journal of hospital pharmacy : science and practice · 2021Article
- Development of an Emergency Revisit Score for Patients With Drug-Related Problems.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021Article
- Effects of hospital pharmacist interventions on health outcomes in older polymedicated inpatients: a scoping review.European geriatric medicine · 2021Article
- Chronic Obstructive Pulmonary Disease Treatment and Pharmacist-Led Medication Management.Drug design, development and therapy · 2021Review
- Current Perceptions and Improvement Approaches of Pharmaceutical Care Capacity of Community Pharmacists: A Quantitative Analysis Based on Survey Data at Chinese Chain Pharmacies.International journal of environmental research and public health · 2020Article
- Promoting clinical pharmacy services through advanced medication review in the emergency department.European journal of hospital pharmacy : science and practice · 2020Observational
- Theoretical model and measurement of shared decision making in web-based pharmaceutical care consultation.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe resolution of potential drug-related problems is a priority of pharmaceutical care programmes.
objectivesTo assess the clinical impact on drug-related negative outcomes of a pharmaceutical care programme focusing on the resolution of potential drug-related problems, initiated in the emergency department for patients with heart failure (HF) and/or chronic obstructive pulmonary disease (COPD).
methodsControlled trials, in which older adults (≥65 years) receiving four or more medications admitted to the emergency department for ≥12 hours for worsening of HF and/or COPD were randomised (1:1) to either a pharmaceutical care programme focusing on resolving potential drug-related problems initiated at the emergency department (intervention group (IG)) or standard care (control group). Comparisons between the groups were made for the proportion of patients with drug-related negative outcomes, number of drug-related negative outcomes per patient, mean stay, patients readmitted within 180 days and 180-day mortality.
results118 patients were included, 59 in each group. Fewer patients in the IG had drug-related negative outcomes (37 (62.7%) vs 47 (79.7%) in the control group (p=0.042)). Fewer drug-related negative outcomes per patient occurred in the IG (56 (0.95 per patient) vs 85 (1.44 per patient) in the control group (p=0.01)). The mean stay was similar between groups (194.7 hours in the IG vs 242.5 hours in the control group (p=0.186)). No difference in revisits within 180 days was found (32 (54.24%) in the IG vs 22 (37.3%) in the control group (p=0.065)). 180-Day mortality was detected in 11 (18.6%) patients in the IG compared with 13 (22%) in the control group (p=0.647).
conclusionA pharmaceutical care programme focusing on resolving potential drug-related problems initiated at the emergency department has a favourable clinical impact, as it reduces the number and prevalence of drug-related negative outcomes. No difference was found in other outcome variables.Trial registration number NCT02368548.
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