ArticleEuropean journal of hospital pharmacy : science and practice2017
Dosage form preference consultation study in children and young adults: paving the way for patient-centred and patient-informed dosage form development.
Article in European journal of hospital pharmacy : science and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Trial
- Choosing the "Ideal" Oral Dosage Form for Pediatric Patients: Parents' Perspectives on Children's Preferences with a Focus on Orodispersible Tablets.Children (Basel, Switzerland) · 2025Article
- Dual-Responsive Ion-Exchange Resin Encapsulated Atomoxetine Hydrochloride for Taste-Masking and Biphasic Release.AAPS PharmSciTech · 2025Article
- Net Promoter Score Model for Evaluating Paediatric Medicine Acceptability: Validation and Feasibility Study.Pharmaceutics · 2024Article
- The impact of patients' preference for pharmaceutical dosage forms on medication discontinuation among patients attending Red Cross pharmacies in Northwest Ethiopia.Scientific reports · 2024Article
- Patients' Preference for Pharmaceutical Dosage Forms: Does It Affect Medication Adherence? A Cross-Sectional Study in Community Pharmacies.Patient preference and adherence · 2024Article
- Colour of Medicines and Children's Acceptability? A Systematic Literature Review of Children's Perceptions about Colours of Oral Dosage Forms.Pharmaceutics · 2023Review
- Potency of Xanthone Derivatives fromMolecules (Basel, Switzerland) · 2023Article
- Taste Masking of Promethazine Hydrochloride Using l-Arginine Polyamide-Based Nanocapsules.Molecules (Basel, Switzerland) · 2023Article
- Nanotechnological innovations in paediatric tuberculosis management: current trends and future prospects.Frontiers in drug delivery · 2023Review
- Data-enriched edible pharmaceuticals (DEEPs): Patients' preferences, perceptions, and acceptability of new dosage forms and their digital aspects - An interview study.Exploratory research in clinical and social pharmacy · 2022Article
- Preference, Perception, and Acceptability of Fluid Gels as a Potential Age-Appropriate Dosage Form for Elderly Patients with Dysphagia.Gels (Basel, Switzerland) · 2022Article
- 3D Printing of Pediatric Medication: The End of Bad Tasting Oral Liquids?-A Scoping Review.Pharmaceutics · 2022Article
- Acceptability of Mebendazole Chewable Tablet in Children Aged 2 to 4 Years in Peru.Pharmaceutics · 2021Article
- I Spy with My Little Eye: A Paediatric Visual Preferences Survey of 3D Printed Tablets.Pharmaceutics · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe current study aims to evaluate dosage form preferences in children and young adults together with identifying the key pragmatic dosage form characteristics that would enable appropriate formulation of orally disintegrating tablets (ODTs).
methodsInternational, multisite, cross-sectional questionnaire of children and young adults aged from 6 to 18 years. Eligibility was based on age, ability to communicate and previous experience in taking medications. The study was carried out at three locations: the UK, Saudi Arabia and Jordan. The questionnaire instrument was designed for participant self-completion under supervision of the study team.
results104 questionnaires were completed by the study cohort (n=120, response rate 87%). Results showed that ODTs were the most preferred oral dosage forms (58%) followed by liquids (20%), tablets (12%) and capsules (11%). The preferred colours were pink or white while the preferred size was small (<8 mm) with a round shape. With regard to flavour, strawberry was the most preferred (30.8%), while orange was the least preferred (5.8%). The results also showed that the most important physical characteristics of ODTs were disintegration time followed by taste, size and flavour, respectively.
conclusionsThe results of our study support the WHO's claim for a shift of paradigm from liquid towards ODTs dosage forms for drug administration to young children older than 6 years. Data from this study will also equip formulators to prioritise development of key physical/performance attributes within the delivery system.
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