Evidence map›Paper›PMID 31156896›Full record

ReviewEuropean journal of hospital pharmacy : science and practice2017

Deprescribing: a primary care perspective.

Polly Duncan, Martin Duerden, Rupert A Payne

Abstract readReview
In one paragraph

Review in European journal of hospital pharmacy : science and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Implementation of a deprescribing guideline by community pharmacists: A focus group study.Exploratory research in clinical and social pharmacy · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Polly DuncanCentre for Academic Primary Care, University of Bristol, Bristol, UK.ORCID 0000-0002-2244-3254
Martin DuerdenCentre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK.
Rupert A PayneCentre for Academic Primary Care, University of Bristol, Bristol, UK.ORCID 0000-0002-5842-4645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polypharmacy is an increasing and global issue affecting primary care. Although sometimes appropriate, polypharmacy can also be problematic, leading to a range of adverse consequences. Deprescribing is the process of supervised withdrawal of an inappropriate medication and has the potential to reduce some of the problems associated with polypharmacy. It is a complex and sensitive process. We examine the issue of deprescribing from the perspective of primary care. Key steps in the deprescribing process are a review of medications and corresponding indications, consideration of harms, assessment of eligibility for discontinuation, prioritisation of medications and implementation of a stopping plan with appropriate monitoring. Patient involvement is a key feature of this process. Deprescribing should be considered in the context of end-of-life care and medication safety, but approaches are also required to identify other situations where deprescribing is appropriate. General practitioners are well positioned to facilitate deprescribing, usually through formal medication review, with decisions informed by a range of other healthcare professionals. Guidelines are available that help guide these processes. A range of studies have explored attitudes towards deprescribing; patients are generally supportive of the concept, although clinician views are varied. The successful implementation of deprescribing strategies still requires important patient and clinician barriers to be overcome, and clinical trial evidence of effectiveness and safety is essential.

Indexed as

DeprescribingGeneral practiceMedication optimisationMedication reviewPolypharmacyPrescribingPRIMARY CARE

Identifiers

PMID31156896
PMCPMC6451545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.