Evidence map›Paper›PMID 31156781›Full record

ReviewIranian journal of basic medical sciences2019

Pharmacological effects of gallic acid in health and diseases: A mechanistic review.

Niloofar Kahkeshani, Fatemeh Farzaei, Maryam Fotouhi, Seyedeh Shaghayegh Alavi, Roodabeh Bahramsoltani, Rozita Naseri, Saeideh Momtaz, Zahra Abbasabadi, Roja Rahimi, Mohammad Hosein Farzaei and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Iranian journal of basic medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 277 papers.

0numbers the graph read from it
0cells of the map it votes in
277citing papers in PubMed
47.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

277 citing papers in PubMed, 633 citations in OpenAlex.

  1. The Added-on ofIranian journal of medical sciences · 2023
    Trial
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  3. Predicting the Toxicity In Silico of the Aqueous Extract ofPharmaceuticals (Basel, Switzerland) · 2026
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217 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Niloofar KahkeshaniDepartment of Pharmacognosy, Faculty of Pharmacy, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Fatemeh FarzaeiPharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Maryam FotouhiStudent Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Seyedeh Shaghayegh AlaviDepartment of Food Science, Engineering and Technology, Faculty of Agricultural Engineering and Technology, University of Tehran, Karaj, Iran.
Roodabeh BahramsoltaniDepartment of Pharmacy in Persian Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Rozita NaseriFaculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Saeideh MomtazMedicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran.
Zahra AbbasabadiPharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Roja RahimiDepartment of Pharmacy in Persian Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hosein FarzaeiPharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Anupam BishayeeLake Erie College of Osteopathic Medicine, Bradenton, FL 34211, USA.
Kermanshah University of Medical Sciences · IRTehran University of Medical Sciences · IRAcademic Center for Education, Culture and Research · IRIran University of Medical Sciences · IRLake Erie College of Osteopathic Medicine · USUniversal Scientific Education and Research Network · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesGallic acid is a natural phenolic compound found in several fruits and medicinal plants. It is reported to have several health-promoting effects. This review aims to summarize the pharmacological and biological activities of gallic acid MATERIALS AND

methodsAll relevant papers in the English language were collected up to June 2018. The keywords of gallic acid, antioxidant, anticancer, antimicrobial, gastrointestinal-, cardiovascular-, metabolic-, neuropsychological-, and miscellaneous- diseases were searched in Google Scholar, PubMed, and Scopus.

resultsSeveral beneficial effects are reported for gallic acid, including antioxidant, anti-inflammatory, and antineoplastic properties. This compound has been reported to have therapeutic activities in gastrointestinal, neuropsychological, metabolic, and cardiovascular disorders.

conclusionCurrent evidence confirms the pharmacological and therapeutic interventions of gallic acid in multiple health complications; however, available data are limited to just cellular and animal studies. Future investigations are essential to further define the safety and therapeutic efficacy of gallic acid in humans.

Indexed as

AnticancerAntioxidantGallic acidHealth benefitsPharmacological effects

Identifiers

PMID31156781
PMCPMC6528712
OpenAlexW2911542696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.