ArticleNature physics2019
Emergence of three-dimensional order and structure in growing biofilms.
Article in Nature physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
140 citing papers in PubMed.
- Physical encounters impose a consistency-amount trade-off on bacterial group formation in marine environments.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Deep learning-based high-information-content graph representation of early stage bacterial biofilms.NPJ biofilms and microbiomes · 2026Article
- Synergistic Inhibitory Effect and Mechanism of Action of Cinnamaldehyde-Carvacrol Nanoemulsion on the Staphylococcus aureus and Escherichia coli Mixed Biofilms Formation.MicrobiologyOpen · 2026Article
- Morphodynamics of surface-attached active drops.Nature communications · 2026Article
- Lives in a gram of soil: linking life cycle biology to soil ecology.The ISME journal · 2026Review
- Spatial structure: shaping the ecology and evolution of microbial communities.FEMS microbiology reviews · 2026Review
- Emergent collective alignment gives competitive advantage to longer cells during range expansion.Nature communications · 2025Article
- Amyloid fibrils of the Als5p-derived peptide NHVirulence · 2025Article
- An agent-based model of metabolic signaling oscillations in Bacillus subtilis biofilms.PLoS computational biology · 2025Article
- Stress-hardening behaviour of biofilm streamers.Nature communications · 2025Article
- Equations describing semi-confluent cell growth (II) colony formation on a flat surface.European biophysics journal : EBJ · 2025Article
- From adhesion to destruction: minocycline's dual action against Cutibacterium acnes biofilms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Review
- Dissecting the physics of bacterial biofilms with agent-based simulations.Current opinion in solid state & materials science · 2025Article
- Reimagining Microbially Induced Concrete Deterioration: A Novel Approach Through Coupled Confocal Laser Scanning Microscope-Avizo Three-Dimensional Modeling of Biofilms.Microorganisms · 2025Article
- Dynamic fluid layer around immotile yeast colonies mediates the spread of bacteria.Biophysical journal · 2025Article
- Colony pattern multistability emerges from a bistable switch.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Segmentation of dense and multi-species bacterial colonies using models trained on synthetic microscopy images.PLoS computational biology · 2025Article
- Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges.Microbiology and molecular biology reviews : MMBR · 2025Review
- Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Surface-attached bacterial biofilms are self-replicating active liquid crystals and the dominant form of bacterial life on earth (1-4). In conventional liquid crystals and solid-state materials, the interaction potentials between the molecules that comprise the system determine the material properties. However, for growth-active biofilms it is unclear whether potential-based descriptions can account for the experimentally observed morphologies, and which potentials would be relevant. Here, we overcame previous limitations of single-cell imaging techniques (5,6) to reconstruct and track all individual cells inside growing three-dimensional (3D) biofilms with up to 10,000 individuals. Based on these data, we identify, constrain, and provide a microscopic basis for an effective cell-cell interaction potential, which captures and predicts the growth dynamics, emergent architecture, and local liquid crystalline order of
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.