Evidence map›Paper›PMID 31156636›Full record

ArticleFrontiers in immunology2019

Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice.

Arnar Gudjonsson, Tor Kristian Andersen, Vibeke Sundvold-Gjerstad, Bjarne Bogen, Even Fossum

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Molecular basis for chemokine recognition and activation of XCR1.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Arnar GudjonssonK.G. Jebsen Centre for Influenza Vaccine Research, Institute of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway.
Tor Kristian AndersenK.G. Jebsen Centre for Influenza Vaccine Research, Institute of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway.
Vibeke Sundvold-GjerstadDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Bjarne BogenK.G. Jebsen Centre for Influenza Vaccine Research, Institute of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway.
Even FossumK.G. Jebsen Centre for Influenza Vaccine Research, Institute of Immunology, Oslo University Hospital, University of Oslo, Oslo, Norway.
University of Oslo · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting antigen to surface receptors on dendritic cells (DCs) can improve antibody response against subunit vaccines. We have previously observed that human XCL1-fusion vaccines target murine Xcr1

Indexed as

AnimalsAntibodies, ViralAntibody FormationChemokines, CDendritic CellsEndocytosisHemagglutinin Glycoproteins, Influenza VirusHumansInfluenza, HumanInfluenza VaccinesMiceMutationOrthomyxoviridae InfectionsRecombinant Fusion ProteinsVaccines, SubunitAntibodies, ViralChemokines, CHemagglutinin Glycoproteins, Influenza Virushemagglutinin, human influenza A virusInfluenza VaccinesRecombinant Fusion ProteinsVaccines, SubunitXcl1 protein, mouseantibody responsecDC1 dendritic cellsDNA vaccinetargetingvaccineXcl1

Identifiers

PMID31156636
PMCPMC6533920
OpenAlexW2946413958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.