Evidence map›Paper›PMID 31156631›Full record

ArticleFrontiers in immunology2019

Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy.

Gary Crispell, Scott P Commins, Stephanie A Archer-Hartman, Shailesh Choudhary, Guha Dharmarajan, Parastoo Azadi, Shahid Karim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 159 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Differential alpha-gal expression duringThe journal of allergy and clinical immunology. Global · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Gary CrispellDepartment of Cell and Molecular Biology, School of Biological, Environment, and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
Scott P ComminsDepartment of Medicine and Pediatrics, University of North Carolina, Chapel Hill, NC, United States.
Stephanie A Archer-HartmanComplex Carbohydrate Research Center, University of Georgia, Athens, GA, United States.
Shailesh ChoudharyDepartment of Medicine and Pediatrics, University of North Carolina, Chapel Hill, NC, United States.
Guha DharmarajanSavannah River Ecology Laboratory, University of Georgia, Aiken, SC, United States.
Parastoo AzadiComplex Carbohydrate Research Center, University of Georgia, Athens, GA, United States.
Shahid KarimDepartment of Cell and Molecular Biology, School of Biological, Environment, and Earth Sciences, The University of Southern Mississippi, Hattiesburg, MS, United States.
University of Georgia · USUniversity of North Carolina at Chapel Hill · USUniversity of Southern Mississippi · USSavannah River National Laboratory · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
TOUGALOO PROTEOMICSP20RR016476 · NCRR · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI SHEARER, GLEN · 2001 to 2011
$30.4M
Understanding alpha-gal red meat allergyR01AI135049 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott Palmer Commins · 2018 to 2026
$5.1M
Orbitrap Fusion Tribrid Mass SpectrometerS10OD018530 · OD · UNIVERSITY OF GEORGIA · PI AZADI, PARASTOO · 2014 to 2014
$750k
NCRR NIH HHS P20 RR016476NIAID NIH HHS R01 AI135049NIGMS NIH HHS P20 GM103476NIH HHS S10 OD018530
6 · The paper itself

Abstract

Development of specific IgE antibodies to the oligosaccharide galactose-α-1, 3-galactose (α-gal) following tick bites has been shown to be the source of red meat allergy. In this study, we investigated the presence of α-gal in four tick species: the lone-star tick (

Indexed as

AllergensAnimalsCells, CulturedFood HypersensitivityGalactoseHumansImmunoglobulin ERed MeatSalivaSalivary GlandsTick-Borne DiseasesTicksAllergensGalactoseImmunoglobulin EAmblyomma americanumglycansIxodes scapularisred meat allergysalivasalivary glandsticksα-gal

Identifiers

PMID31156631
PMCPMC6533943
OpenAlexW2941274011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.