Evidence map›Paper›PMID 31156612›Full record

ArticleFrontiers in immunology2019

Immunomodulatory Effects and Induction of Apoptosis by Different Molecular Weight Chitosan Oligosaccharides in Head Kidney Macrophages From Blunt Snout Bream (

Changsong Wu, Yishan Dai, Gailing Yuan, Jianguo Su, Xiaoling Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Changsong WuDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Yishan DaiDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Gailing YuanDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Jianguo SuDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Xiaoling LiuDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prophylactic administration of immunopotentiators has been tested and practiced as one of the most promising disease prevention methods in aquaculture. Chitosan oligosaccharide (COS), as an ideal immunopotentiator, is mainly used as feed additives in aquaculture, and the antimicrobial and immune enhancement effects are highly correlated with molecular weight (MW), but little is known about the mechanisms in teleost. Here, we isolated and purified macrophages in head kidney from blunt snout bream (

Indexed as

AnimalsApoptosisChitosanCypriniformesFish ProteinsGene Expression RegulationHead KidneyImmunologic FactorsMacrophage ActivationMacrophagesMolecular WeightOligosaccharidesReal-Time Polymerase Chain ReactionSequence Analysis, RNASignal TransductionTranscriptomeChitosanFish ProteinsImmunologic FactorsOligosaccharidesTumor Suppressor Protein p53apoptosisChitosan oligosaccharidemacrophageMegalobrama amblycephalaP53 pathwaytranscriptome

Identifiers

PMID31156612
PMCPMC6530513
OpenAlexW2944905613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.