ReviewFrontiers in microbiology2019
Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants.
Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 211 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
211 citing papers in PubMed.
- Plaque Removal and Gingival Bleeding Using Biodegradable Toothbrushes: Salvadora persica, Bamboo, and Nylon: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Trial
- Effective Abatement of Multidrug-resistant Pathogens Employing Natural Polyphenols and Polyphenol-based Formulations: A Systematic Review and Integrated Network Pharmacology Approach.Applied biochemistry and biotechnology · 2026Review
- Antibacterial, Phytochemical, and Antioxidant Properties of Propolis Extracts Obtained Using Different Solvents Against Multidrug-Resistant Bacteria.Pathogens (Basel, Switzerland) · 2026Article
- Plant antimicrobials: extraction, characterization and activity against foodborne microorganisms.Folia microbiologica · 2026Review
- Alkaloid-based nanodrug delivery systems: An emerging strategy against drug-resistant bacterial wound infections.International journal of pharmaceutics: X · 2026Review
- Identification of antigonorrhoeal phytochemical lead compounds using a metabolomics-guided approach.Folia microbiologica · 2026Article
- LC-MS/MS-Based Comparative Phytochemical Profiling and Multivariate (PCA) Analysis of Seed Extracts fromInternational journal of molecular sciences · 2026Article
- Preliminary phytochemical profiling and in vitro antibacterial activity of Lycium edgeworthii (Solanaceae) leaf extract against multidrug-resistant bacterial pathogens.Scientific reports · 2026Article
- Natural Antimicrobials from Plants Used as Food Preservatives.Foods (Basel, Switzerland) · 2026Review
- Natural Alkaloids as Antimicrobial Agents: Mechanisms, Potentials and Challenges.Molecules (Basel, Switzerland) · 2026Review
- Synergistic Interaction Between Alkanna tinctoria (L.) Tausch and Cefixime Enhances Antibacterial Activity Against Resistant Bacterial Strains.Current microbiology · 2026Article
- A critical review on the roles of natural products in shaping oral microbiota and preventing chronic diseases.Natural products and bioprospecting · 2026Review
- Isolation, RP-UHPLC-ESI-LIT-Orbitrap-MS/MS-Based Metabolic Profiling and Anticandidal Activity of the Root and Leaf Secondary Metabolites of Monotes Kerstingii Gilg (Dipterocarpaceae).Chemistry & biodiversity · 2026Article
- Edible Potential ofFood science & nutrition · 2026Article
- Integrated foodomics and network pharmacology reveal functional food potential in tatsoi microgreens and baby greens.NPJ science of food · 2026Article
- A chromosome-level genome assembly and multi-omics analyses provide insights into the biosynthesis of piperlongumine in Piper sarmentosum.Communications biology · 2026Article
- Article
- Bottle Gourd (Scientifica · 2026Article
- Phytochemistry, Antimicrobial, Analgesic, Antibiofilm, Diuretic Activities, and Acute Toxicity of Bark Extracts From Three Plants (Khaya senegalensis, Ocimum americanum, and Cassytha filiformis) Collected in Benin.TheScientificWorldJournal · 2026Article
- Article
151 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic-resistant microorganisms have been an ever-growing concern over the past years. This has led researchers to direct their attention onto plants to be able to discover new possible antimicrobial compounds. The Middle East encompasses a wide spectrum of plant diversity with over 20,000 different species in habitats ranging from deserts to snow-capped mountains. Several plant secondary metabolites and their derivatives have been identified as possible antimicrobial agents. Among the secondary metabolites studied, alkaloids and polyphenols have shown strong antimicrobial activity. Polyphenols are one of the most numerous and diverse group of secondary metabolites; their antioxidant properties provide the basis for antimicrobial effects. Alkaloids provided the underlying structure for the development of several antibiotics with a diverse range of action. The ability of some plant secondary metabolites to act as resistance-modifying agents is a promising field in mitigating the spread of bacterial resistance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.