ArticleFrontiers in psychiatry2019
Negative Mood Induction Increases Choice of Heroin Versus Food Pictures in Opiate-Dependent Individuals: Correlation With Self-Medication Coping Motives and Subjective Reactivity.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05047627 (Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Ultra-brief breath counting (mindfulness) training promotes recovery from stress-induced alcohol-seeking in student drinkers.Addictive behaviors · 2020Trial
- Negative affect-driven impulsivity as hierarchical model-based overgeneralization.Trends in cognitive sciences · 2025Review
- Evaluating a mobile app's effects on depression and anxiety in medication-treated opioid use disorder.Npj mental health research · 2024Article
- Age moderates the association of optimism on craving during substance use disorder treatment.Journal of substance use and addiction treatment · 2024Article
- Investigating mood-modification, withdrawal, and sensitization in compulsive sexual behaviour.Frontiers in psychiatry · 2024Article
- Neural circuits controlling choice behavior in opioid addiction.Neuropharmacology · 2023Review
- A neuroeconomic signature of opioid craving: How fluctuations in craving bias drug-related and nondrug-related value.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Modulation of Attentional Bias to Drug and Affective Cues by Therapeutic and Neuropsychological Factors in Patients With Opioid Use Disorder on Methadone Maintenance Therapy.Frontiers in psychiatry · 2021Article
- Relative expected value of drugs versus competing rewards underpins vulnerability to and recovery from addiction.Behavioural brain research · 2020Review
- Does acute stress influence the Pavlovian-to-instrumental transfer effect? Implications for substance use disorders.Psychopharmacology · 2020Article
- Contribution of alcohol- and cigarette-related cues to concurrent reinforcer choice in humans.Behavioural processes · 2020Article
- Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute growth in negative affect is thought to play a major role in triggering relapse in opiate-dependent individuals. Consistent with this view, three lab studies have demonstrated that negative mood induction increases opiate craving in opiate-dependent individuals. The current study sought to confirm these effects with a behavioral measure of heroin seeking, and test whether the effect is associated with self-reported opiate use to cope with negative affect and subjective reactivity to mood induction. Participants were heroin-dependent individuals engaged with treatment services (n = 47) and control participants (n = 25). Heroin users completed a questionnaire assessing reasons for using heroin: negative affect, social pressure, and cued craving. Baseline heroin choice was measured by preference to enlarge heroin versus food thumbnail pictures in two-alternative forced-choice trials. Negative mood was then induced by depressive statements and music before heroin choice was tested again. Subjective reactivity was indexed by negative and positive mood reported at the pre-induction to post-test timepoints. Heroin users chose heroin images more frequently than controls overall (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.