ReviewFrontiers in physiology2019
Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety.
Erratum issued 16 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph
Review in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 16 registered trials, which are not on this map. Cited by 429 papers, 14 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
429citing papers in PubMed, 14 pooled it
92.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects on Muscle Strength After Blood Flow Restriction Resistance Exercise (BFR-RE) in Early In-patient Rehabilitation of Chronic Obstructive Pulmonary Disease Acute Exacerbation (COPDAE), a Single Blinded, Randomized Controlled Study
The Effect Of Blood Flow Restrıcted Resistive And Aerobic Exercises in Chronic Obstructive Pulmonary Patients
Systemic Effects of A Continuous Blood Flow Restricted Aerobic Exercise Session in COPD Patients: A Randomised Controlled Trial.
The Effects of Bone Health on Landing Mechanics on Patients Post ACL Reconstruction.
The Influence of Restriction Pressure on Indices of Exercise-Induced Muscle Damage Following Low-Load Blood Flow-Restricted Resistance Exercise: A Randomised Controlled Trial in Healthy Adults
Effects of Blood Flow Restriction Resistance Exercise on Strength and Transfer in Lower Cervical Spinal Cord Injury Patients
Effects of Low-intensity Blood-flow Restricted Exercise Compared to Standard Rehabilitation in Patients With Knee Osteoarthritis - a Randomized Controlled Trial
The Acute Effect of Upper Limb Low Load Blood Flow Restriction Training (BFRT) on Hypoalgesia. A Randomized Controlled Trial
Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients
Effect of Blood Flow Restriction on Pain Perception, Grip Strength and Nerve Conductivity in Patients With Carpal Tunnel Syndrome: A Randomized Controlled Trial.
The Short-term Effect of Low-load Resistance Training with Blood-flow Restriction on Somatosensory-evoked Potentials in Healthy Young Adults - a Randomized Crossover Trial
Comparing the Effectiveness of Blood Flow Restriction Therapy Versus Standard Exercise After Arthroscopic Rotator Cuff Repair: Protocol for the Multicenter S-TRONGER Randomized Controlled Trial
Exercise-induced Hypoalgesia Following Blood Flow Restriction in Rotator Cuff Repair Rehabilitation: a Randomized Crossover Clinical Trial
Effect of Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction
NCT07315425 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation
Investigation of the Acute Effects of Blood Flow Restriction Aerobic Exercise on Hemodynamic Responses and Muscle Oxygen in Patients With Interstitial Lung Disease
The Effects Of Combining Blood Flow Restriction Therapy With Extracorporeal Shock Wave Therapy On Pain, Muscle Strength, And Functional Outcomes İn Patients Diagnosed With Lateral Epicondylitis: a Randomized Controlled Trial
Who cites it
429 citing papers in PubMed, 14 syntheses or guidelines pooled it, 799 citations in OpenAlex.
- Effectiveness and safety of blood flow restriction training for patients with type 2 diabetes mellitus: a systematic review with meta analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effects of blood flow restriction training on cardiovascular autonomic function in middle-aged and older adults: a meta-analysis.Scientific reports · 2026Pooled it
- Quantitative assessment of efficacy and evaluation of feasibility of exercise training protocols in adult and pediatric primary mitochondrial disease.BMC medicine · 2026Pooled it
- Effectiveness of Blood Flow Restriction Training in Neurological Rehabilitation: A Systematic Review and Meta-analysis.Sports medicine - open · 2026Pooled it
- Efficacy of blood flow restriction training in chronic ankle conditions: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Effects of combined blood flow restriction and neuromuscular electrical stimulation on skeletal muscle hypertrophy in adults: a systematic review and meta analysis.Scientific reports · 2026Pooled it
- Can blood flow restriction amplify the physiological and performance benefits of interval training in male intermittent-sport athletes? a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Comparative effectiveness of resistance training modalities after anterior cruciate ligament reconstruction: a network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Pooled it
- The effects of lower limb blood flow restriction training on post-activation potentiation enhancement and fatigue: a meta-analysis.Frontiers in physiology · 2026Pooled it
- Blood Flow Restriction Training in Knee Arthroplasty: A Systematic Review of Current Evidence on Postoperative Muscle Strength and Function.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Does Protocol Matter for Repetition Volume? A Meta-Analytic Investigation of Volitional Failure Versus the Traditionally Used 75-Repetition Blood Flow Restriction Resistance Training.Sports medicine - open · 2025Pooled it
- Systematic review and meta-analysis of the effects of blood flow restriction training on bone health in older adults.Scientific reports · 2025Pooled it
- Effects of blood flow restriction combined with high-load training on muscle strength and sports performance in athletes: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Comparison of Blood Flow Restriction Interventions to Standard Rehabilitation After an Anterior Cruciate Ligament Injury: A Systematic Review.The American journal of sports medicine · 2024Pooled it
- Personalized blood flow restriction training at variable occlusion pressures improves multisystem function in overweight and obese older women.European journal of applied physiology · 2026Trial
- Inter-Set Blood-Flow Restriction Increases Peripheral Physiological Stress While Preserving Repeated-Sprint Mechanical Output in Trained Athletes.European journal of sport science · 2026Trial
- Effects of Blood Flow Restriction Training at Different Levels of Arterial Occlusion Pressure on Body Composition and Athletic Performance in Youth Soccer Players: A Randomized Controlled Trial.Journal of sports science & medicine · 2026Trial
- Acute neuromuscular and metabolic responses to a novel low-load combined isometric and isotonic resistance training protocol.European journal of applied physiology · 2026Trial
- The Acute Effects of Blood Flow Restriction on Ankle Muscle Reaction Time and Proprioception in Healthy Individuals.Journal of sports science & medicine · 2026Trial
- Ischaemic pre-conditioning improves workload, fatigue and recovery in team sport: A randomized, double-blind, placebo-controlled crossover trial.Experimental physiology · 2026Trial
369 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
14 authors at 9 institutions in 7 countries.
Stephen D PattersonFaculty of Sport, Health and Applied Sciences, St Marys University, London, United Kingdom.
Luke HughesFaculty of Sport, Health and Applied Sciences, St Marys University, London, United Kingdom.
Stuart WarmingtonSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, VIC, Australia.
Jamie BurrDepartment of Human Health and Nutritional Science, University of Guelph, Guelph, ON, Canada.
Brendan R ScottMurdoch Applied Sports Science Laboratory, Discipline of Exercise Science, Murdoch University, Perth, WA, Australia.
Johnny OwensOwens Recovery Science, San Antonio, TX, United States.
Takashi AbeDepartment of Health, Exercise Science, and Recreation Management, Kevser Ermin Applied Physiology Laboratory, University of Mississippi, Oxford, MS, United States.
Jakob L NielsenDepartment of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Cleiton Augusto LibardiMUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Federal University of São Carlos (UFSCar), São Carlos, Brazil.
Gilberto LaurentinoSchool of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.
Gabriel Rodrigues NetoCoordination of Physical Education/Professional Master's in Family Health, Nursing and Medical Schools, Nova Esperança (FAMENE/FACENE), João Pessoa, Brazil.
Christopher BrandnerSport Science Department, Aspire Academy for Sports Excellence, Doha, Qatar.
Juan Martin-HernandezI+HeALTH Research Group, Department of Health Sciences, Faculty of Health Sciences, Miguel de Cervantes European University, Valladolid, Spain.
Jeremy LoennekeDepartment of Health, Exercise Science, and Recreation Management, Kevser Ermin Applied Physiology Laboratory, University of Mississippi, Oxford, MS, United States.
University of Mississippi · USAspire Academy · QADeakin University · AUMurdoch University · AUUniversidade de São Paulo · BRUniversidade Federal de São Carlos · BRUniversidad Europea Miguel de Cervantes · ESUniversity of Guelph · CAUniversity of Southern Denmark · DK
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current manuscript sets out a position stand for blood flow restriction (BFR) exercise, focusing on the methodology, application and safety of this mode of training. With the emergence of this technique and the wide variety of applications within the literature, the aim of this position stand is to set out a current research informed guide to BFR training to practitioners. This covers the use of BFR to enhance muscular strength and hypertrophy via training with resistance and aerobic exercise and preventing muscle atrophy using the technique passively. The authorship team for this article was selected from the researchers focused in BFR training research with expertise in exercise science, strength and conditioning and sports medicine.
Indexed as
BFR exerciseblood flow restriction exercisekaatsu trainingocclusion trainingresistance training
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT04448236ClinicalTrials.gov
NCT04521959ClinicalTrials.gov
NCT04526184ClinicalTrials.gov
NCT04682392ClinicalTrials.gov
NCT05037942ClinicalTrials.gov
NCT05425238ClinicalTrials.gov
and 10 more above
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.