Evidence map›Paper›PMID 31156363›Full record

SynthesisFrontiers in neuroscience2019

Increased Serum S100B Levels in Patients With Epilepsy: A Systematic Review and Meta-Analysis Study.

Kai-Ge Liang, Rong-Zheng Mu, Yu Liu, Dan Jiang, Tian-Tian Jia, Yao-Jiang Huang

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05450822 (The BrainDrugs-Epilepsy Study), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05450822 recruitingnot on this mapstarted 2022, after this paper: background citation

The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy

TypeobservationalSponsorGitte Moos KnudsenRan2022 to 2031Enrolled550ConditionsEpilepsyArmsLevetiracetam, Levetiracetam Tablets, Lamotrigine tablet
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Circulating microRNAs as Biomarkers of Various Forms of Epilepsy.Medical sciences (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Integrated virtual screening, molecular modeling and machine learning approaches revealed potential natural inhibitors for epilepsy.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  18. Review
  19. The S100B Protein: A Multifaceted Pathogenic Factor More Than a Biomarker.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Kai-Ge LiangCollege of Life and Environmental Sciences, Minzu University of China, Beijing, China.
Rong-Zheng MuCollege of Equipment Management and UAV Engineering, Air Force Engineering University, Xian, China.
Yu LiuJarud Banner Agriculture and Animal Husbandry Bureau, Tongliao, China.
Dan JiangBeijing Engineering Research Center of Food Environment and Public Health, Minzu University of China, Beijing, China.
Tian-Tian JiaCollege of Life and Environmental Sciences, Minzu University of China, Beijing, China.
Yao-Jiang HuangCollege of Life and Environmental Sciences, Minzu University of China, Beijing, China.
Minzu University of China · CNAir Force Engineering University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epilepsylevelmeta-analysisS100Bserum

Identifiers

PMID31156363
PMCPMC6532535
OpenAlexW2946806912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.