Evidence map›Paper›PMID 31156361›Full record

ArticleFrontiers in neuroscience2019

Test-Retest Reliability of the Effects of Continuous Theta-Burst Stimulation.

Ali Jannati, Peter J Fried, Gabrielle Block, Lindsay M Oberman, Alexander Rotenberg, Alvaro Pascual-Leone

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Review
  11. Article
  12. Article
  13. Biomarkers Obtained by Transcranial Magnetic Stimulation in Neurodevelopmental Disorders.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2022
    Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Modulation of motor cortical excitability by continuous theta-burst stimulation in adults with autism spectrum disorder.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Article
  19. Transcranial Random Noise Stimulation Acutely Lowers the Response Threshold of Human Motor Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Ali JannatiBerenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Peter J FriedBerenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Gabrielle BlockBerenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Lindsay M ObermanNeuroplasticity and Autism Spectrum Disorder Program, Department of Psychiatry and Human Behavior, E.P. Bradley Hospital, Warren Alpert Medical School, Brown University, East Providence, RI, United States.
Alexander RotenbergBerenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Alvaro Pascual-LeoneBerenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Beth Israel Deaconess Medical Center · USBerenson Allen Center for Noninvasive Brain Stimulation · USBoston Children's Hospital · USBradley Hospital · USUniversitat Autònoma de Barcelona · ES

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
Transcranial Direct Current Stimulation and Robotic Training in Chronic StrokeR01HD069776 · NICHD · WINIFRED MASTERSON BURKE MED RES INST · PI EDWARDS, DYLAN JAMES · 2012 to 2016
$3.2M
Cortical Plasticity in Autism Spectrum DisordersR01MH100186 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ROTENBERG, ALEXANDER · 2014 to 2018
$2.2M
Mapping progressive loss of intracortical inhibition by TMS and EEG in posttraumatic epileptogenesisR01NS088583 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI ROTENBERG, ALEXANDER · 2015 to 2019
$1.9M
Cortical connectivity, physiology, and response to stimulation in human epilepsyR01NS073601 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CHANG, BERNARD S. · 2011 to 2015
$1.9M
Role of functional brain connectivity on efficacy of TMS for depressionR21MH099196 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PASCUAL-LEONE, ALVARO · 2013 to 2014
$491k
Brain Plasticity Measures in MCIR21AG051846 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PASCUAL-LEONE, ALVARO · 2016 to 2017
$476k
Transcranial Stimulation in Spino-Cerebellar AtaxiaR21NS085491 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PASCUAL-LEONE, ALVARO · 2013 to 2014
$469k
NCRR NIH HHS UL1 RR025758NIA NIH HHS R21 AG051846NICHD NIH HHS R01 HD069776NIMH NIH HHS R01 MH100186NIMH NIH HHS R21 MH099196NINDS NIH HHS R01 NS073601NINDS NIH HHS R01 NS088583NINDS NIH HHS R21 NS085491
6 · The paper itself

Abstract

objectivesThe utility of continuous theta-burst stimulation (cTBS) as index of cortical plasticity is limited by inadequate characterization of its test-retest reliability. We thus evaluated the reliability of cTBS aftereffects, and explored the roles of age and common single-nucleotide polymorphisms in the brain-derived neurotrophic factor (

methodsTwenty-eight healthy adults (age range 21-65) underwent two identical cTBS sessions (median interval = 9.5 days) targeting the motor cortex. Intraclass correlation coefficients (ICCs) of the log-transformed, baseline-corrected amplitude of motor evoked potentials (ΔMEP) at 5-60 min post-cTBS (T5-T60) were calculated. Adjusted effect sizes for cTBS aftereffects were then calculated by taking into account the reliability of each cTBS measure.

resultsΔMEP at T50 was the most-reliable cTBS measure in the whole sample (ICC = 0.53). Area under-the-curve (AUC) of ΔMEPs was most reliable when calculated over the full 60 min post-cTBS (ICC = 0.40). cTBS measures were substantially more reliable in younger participants (< 35 years) and in those with

conclusioncTBS aftereffects are most reliable when assessed 50 min post-cTBS, or when cumulative ΔMEP measures are calculated over 30-60 min post-cTBS. Reliability of cTBS aftereffects is influenced by age, and

Indexed as

APOEBDNFcontinuous theta-burst stimulationplasticityreliabilitytranscranial magnetic stimulation

Identifiers

PMID31156361
PMCPMC6533847
OpenAlexW2946175450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.