ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2019
Frontoinsular Network Markers of Current and Future Adolescent Mood Health.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Neurocognitive Biotypes of Risk and Resilience for Mood Disorders in Adolescents: Insights From Behavioral and Graph-Theoretic Network Markers.Biological psychiatry global open science · 2025Article
- Zhi-zi-chi decoction mitigates depression by enhancing lncRNA Six3os1 expression and promoting histone H3K4 methylation at the BDNF promoter.Journal of cellular and molecular medicine · 2024Article
- Neurocognitive risk phenotyping to predict mood symptoms in adolescence.Journal of psychopathology and clinical science · 2024Article
- Dense Sampling Approaches for Psychiatry Research: Combining Scanners and Smartphones.Biological psychiatry · 2023Review
- Multimodal Investigations of Reward Circuitry and Anhedonia in Adolescent Depression.Frontiers in psychiatry · 2021Review
- Amygdala functional connectivity in the acute aftermath of trauma prospectively predicts severity of posttraumatic stress symptoms.Neurobiology of stress · 2020Article
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10 authors at 4 institutions in 1 country.
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Abstract
backgroundAdolescence is a developmental period in which depression and related mood syndromes often emerge, but few objective markers exist to guide diagnosis or predict symptoms. One potential mood marker is the functioning of frontoinsular networks, which undergo substantial development in adolescence and have been implicated in adult depression. To test this hypothesis, we used task-based neuroimaging to evaluate whether frontoinsular network dysfunction was linked to current and prospective mood health in adolescents.
methodsAdolescents (n = 40, 13-19 years of age) reporting varying levels of depressive symptom severity performed an emotional working memory task with neuroimaging. Next, teens completed a 2-week follow-up consisting of a daily diary report of negative affect and final report of depressive symptoms (n = 28 adherent). Analyses tested associations between task-related functional connectivity in frontoinsular networks and baseline or prospective measures of mood health over 2-week follow-up.
resultsFrontoinsular task response was associated with higher current depression severity (p = .049, η
conclusionsThese findings indicate that frontoinsular imbalances are related to both current depression and changes in mood health in the near future and suggest that frontoinsular markers may hold promise as translational tools for risk prediction.
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