ArticleCurrent biology : CB2019
Olfactory and Neuromodulatory Signals Reverse Visual Object Avoidance to Approach in Drosophila.
Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 58 citations in OpenAlex.
- Cellular and functional dissection of the octopaminergic and tyraminergic system in the Drosophila brain.Current biology : CB · 2026Article
- Odor tracking in flyingProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Odor tracking in flyingbioRxiv : the preprint server for biology · 2026Article
- Ecological cues orchestrate concerted courtship in abioRxiv : the preprint server for biology · 2025Article
- Serotonin selectively modulates visual responses of object motion detectors inJournal of neurophysiology · 2025Article
- Extinction of Innate Floral Preferences in the Generalist Solitary Pollinator Eristalis tenax.Journal of chemical ecology · 2025Article
- Serotonin selectively modulates visual responses of object motion detectors inbioRxiv : the preprint server for biology · 2025Article
- Innate visual attraction before, during and after escape from adverse substrates in carpenter ants.The Journal of experimental biology · 2025Article
- Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion.PLoS biology · 2024Article
- Optokinetic response in D. melanogaster reveals the nature of common repellent odorants.Scientific reports · 2024Article
- Mosquitoes integrate visual and acoustic cues to mediate conspecific interactions in swarms.Current biology : CB · 2024Article
- Constitutive and Conditional Epitope Tagging of Endogenous G-Protein-Coupled Receptors inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Elevated sleep quota in a stress-resilient Drosophila species.Current biology : CB · 2024Article
- Female Aedes aegypti mosquitoes use communal cues to manage population density at breeding sites.Communications biology · 2024Article
- Neural mechanisms to incorporate visual counterevidence in self-movement estimation.Current biology : CB · 2023Article
- Threat gates visual aversion via theta activity in Tachykinergic neurons.Nature communications · 2023Article
- Regulation and modulation of biogenic amine neurotransmission inFrontiers in physiology · 2023Review
- Carbon dioxide and blood-feeding shift visual cue tracking during navigation inBiology letters · 2022Article
- Review
- Correlated decision making across multiple phases of olfactory-guided search in Drosophila improves search efficiency.The Journal of experimental biology · 2021Article
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3 authors at 1 institution in 1 country.
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Abstract
Behavioral reactions of animals to environmental sensory stimuli are sometimes reflexive and stereotyped but can also vary depending on contextual conditions. Engaging in active foraging or flight provokes a reversal in the valence of carbon dioxide responses from aversion to approach in Drosophila [1, 2], whereas mosquitoes encountering this same chemical cue show enhanced approach toward a small visual object [3]. Sensory plasticity in insects has been broadly attributed to the action of biogenic amines, which modulate behaviors such as olfactory learning, aggression, feeding, and egg laying [4-14]. Octopamine acts rapidly upon the onset of flight to modulate the response gain of directionally selective motion-detecting neurons in Drosophila [15]. How the action of biogenic amines might couple sensory modalities to each other or to locomotive states remains poorly understood. Here, we use a visual flight simulator [16] equipped for odor delivery [17] to confirm that flies avoid a small contrasting visual object in odorless air [18] but that the same animals reverse their preference to approach in the presence of attractive food odor. An aversive odor does not reverse object aversion. Optogenetic activation of either octopaminergic neurons or directionally selective motion-detecting neurons that express octopamine receptors elicits visual valence reversal in the absence of odor. Our results suggest a parsimonious model in which odor-activated octopamine release excites the motion detection pathway to increase the saliency of either a small object or a bar, eliciting tracking responses by both visual features.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.