ArticleThyroid : official journal of the American Thyroid Association2019
Afirma Gene Sequencing Classifier Compared with Gene Expression Classifier in Indeterminate Thyroid Nodules.
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In one paragraph
Article in Thyroid : official journal of the American Thyroid Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.
0numbers the graph read from it
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51citing papers in PubMed, 6 pooled it
12.0field-weighted citation impact, top 1% of its field
What it found
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Who cites it
51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Impact of Molecular Testing on Surgical Decision-Making in Indeterminate Thyroid Nodules: A Global Meta-Analysis Across Test Generations.Endocrine pathology · 2026Pooled it
- Comparing the diagnostic accuracy of Afirma GSC to ThyroSeq V3 in cytologically indeterminate thyroid nodules.European thyroid journal · 2025Pooled it
- Real-World Performance of the Afirma Genomic Sequencing Classifier (GSC)-A Meta-analysis.The Journal of clinical endocrinology and metabolism · 2023Pooled it
- Assessing Bias and Limitations of Clinical Validation Studies of Molecular Diagnostic Tests for Indeterminate Thyroid Nodules: Systematic Review and Meta-Analysis.Thyroid : official journal of the American Thyroid Association · 2022Pooled it
- Impact of Molecular Testing on the Management of Indeterminate Thyroid Nodules Among Western and Asian Countries: a Systematic Review and Meta-analysis.Endocrine pathology · 2021Pooled it
- Thyroseq v3, Afirma GSC, and microRNA Panels Versus Previous Molecular Tests in the Preoperative Diagnosis of Indeterminate Thyroid Nodules: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Molecular Testing for Thyroid Nodules of Indeterminate Cytology: A Health Technology Assessment.Ontario health technology assessment series · 2022Trial
- A Novel Risk Stratification System for Thyroid Nodules With Indeterminate Cytology-A Pilot Cohort Study.Frontiers in endocrinology · 2020Trial
- The Diagnostic Performance of Afirma Genomic Sequencing Classifier in Black and Hispanic Patients With Indeterminate Thyroid Nodules.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Distinct molecular profiles of indeterminate and malignant thyroid nodules in patients under 21 years of age.Endocrine-related cancer · 2026Article
- Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Risk of malignancy and necessity of completion thyroidectomy in patients with indeterminate thyroid nodules (Bethesda III and IV), more than expected in endemic region.Updates in surgery · 2026Article
- Artificial intelligence in thyroid nodules and cancer: clinical validation and real-world performance.Endocrine connections · 2026Article
- Afirma genomic sequencing classifier performance in young patients with cytologically indeterminate thyroid nodules.The Journal of clinical endocrinology and metabolism · 2026Article
- Utility of genomic sequencing classifier in managing cytologically indeterminate oncocytic thyroid nodules.The Journal of clinical endocrinology and metabolism · 2026Article
- The actual and future role of molecular tests in thyroid pathology.Virchows Archiv : an international journal of pathology · 2026Review
- Comparing the diagnostic accuracy of pre-operative genetic testing for thyroid cancer on fine needle aspiration cytology specimens: a systematic review and meta-analysis of diagnostic accuracy.Discover oncology · 2025Article
- Great Debate: Molecular Testing and Extent of Surgery in Well-Differentiated Thyroid Cancer.Annals of surgical oncology · 2025Article
- Development and validation of mRNA expression-based classifiers to predict low-risk thyroid tumors.Frontiers in endocrinology · 2025Article
- Diagnostic accuracy of Afirma gene expression classifier, Afirma gene sequencing classifier, ThyroSeq v2 and ThyroSeq v3 for indeterminate (Bethesda III and IV) thyroid nodules: a meta-analysis.Endocrine connections · 2024Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 2 countries.
Mayumi Endo1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Fadi Nabhan1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Kyle Porter2Department of Biomedical Informatics, Center for Biostatistics and Bioinformatics, The Ohio State University, Columbus, Ohio.
Katie Roll1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Lawrence A Shirley3Division of Surgical Oncology; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Irina Azaryan1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Dena Tonkovich4Division of Pathology, The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Jeanette Perlick1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Laura E Ryan1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Raheela Khawaja1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Shumei Meng1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
John E Phay3Division of Surgical Oncology; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Matthew D Ringel1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Jennifer A Sipos1Division of Endocrinology, Diabetes, and Metabolism; The Ohio State University and Arthur G. James Cancer Center, Columbus, Ohio.
Diabetes Australia · AUThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · USThe Ohio State University · US
Funding
Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3MThe Ohio State University and MD Anderson Cancer Center Thyroid Cancer SPOREP50CA168505 · NCI · OHIO STATE UNIVERSITY · PI DE LA CHAPELLE, ALBERT · 2013 to 2017
$10.9MNCI NIH HHS P30 CA016058NCI NIH HHS P50 CA168505
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gene Expression ProfilingSequence Analysis, DNAAdenocarcinoma, FollicularAdenoma, OxyphilicAdultAgedBiopsy, Fine-NeedleCarcinoma, PapillaryFemaleGene ExpressionHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesThyroid Cancer, PapillaryAfirmaindeterminate thyroid nodulesmolecular diagnostic testing
Identifiers
What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.