Evidence map›Paper›PMID 31154869›Full record

ReviewExpert review of medical devices2019

In Vitro models for thrombogenicity testing of blood-recirculating medical devices.

Deepika N Sarode, Shuvo Roy

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of medical devices, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Standardization of In-Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026
    Guideline
  2. Standardization ofPerfusion · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. In Vitro Thrombogenicity Evaluation of Hemodialyzers.International journal of molecular sciences · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Platelet Adhesion and Activation in an ECMO Thrombosis-on-a-Chip Model.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  11. Article
  12. PreclinicalFrontiers in bioengineering and biotechnology · 2023
    Review
  13. Strategies for surface coatings of implantable cardiac medical devices.Frontiers in bioengineering and biotechnology · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Deepika N Sarodea Department of Bioengineering and Therapeutic Sciences , University of California , San Francisco , CA , USA.
Shuvo Roya Department of Bioengineering and Therapeutic Sciences , University of California , San Francisco , CA , USA.
University of California, San Francisco · US

Funding

UCSF-Stanford Center of Excellence in Regulatory Science and InnovationU01FD005978 · FDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALTMAN, RUSS BIAGIO, GIACOMINI, KATHLEEN M · 2016 to 2025
$34.5M
Building an Implantable Artificial KidneyU01EB021214 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FISSELL, WILLIAM H, ROY, SHUVO · 2015 to 2018
$6.0M
UCSF-Stanford Center of Excellence in Regulatory Science and InnovationU01FD004979 · FDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALTMAN, RUSS BIAGIO, GIACOMINI, KATHLEEN M · 2014 to 2016
$5.4M
Implantable Bio-Artificial Pancreas (iBAP)U01EB025136 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROY, SHUVO · 2017 to 2021
$3.2M
FDA HHS U01 FD004979FDA HHS U01 FD005978NIBIB NIH HHS U01 EB021214NIBIB NIH HHS U01 EB025136
6 · The paper itself

Abstract

introductionBlood-recirculating medical devices, such as mechanical circulatory support (MCS), extracorporeal membrane oxygenators (ECMO), and hemodialyzers, are commonly used to treat or improve quality of life in patients with cardiac, pulmonary, and renal failure, respectively. As part of their regulatory approval, guidelines for thrombosis evaluation in pre-clinical development have been established. AREAS COVERED: This review focuses on EXPERT OPINION: In general, researchers have favored

Indexed as

Equipment and SuppliesModels, BiologicalBiocompatible MaterialsBiomarkersHumansQuality of LifeThrombosisBiocompatible MaterialsBiomarkersBlood compatibilityblood-recirculating medical devicesdynamic thrombosis modelshemocompatibility modelsstatic thrombosis modelsthrombogenicitythrombosis

Identifiers

PMID31154869
PMCPMC6660015
OpenAlexW2947092447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.