Evidence map›Paper›PMID 31154573›Full record

ArticleAnnals of nuclear medicine2019

Novel 3D heart left ventricle muscle segmentation method for PET-gated protocol and its verification.

Tomasz Kubik, Krzysztof Kałużyński, Cyrill Burger, Alessandro Passeri, Selene Margiacchi, Paola Saletti, Rita Bonini, Elena Lorenzini, Roberto Sciagrà

Open access · hybridAbstract read
In one paragraph

Article in Annals of nuclear medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Tomasz KubikFaculty of Mechatronics, Institute for Metrology and Biomedical Engineering, Warsaw University of Technology, ul. św. Andrzeja Boboli 8, 02-525, Warsaw, Poland. t.kubik@mchtr.pw.edu.pl.ORCID http://orcid.org/0000-0002-9822-1316
Krzysztof KałużyńskiFaculty of Mechatronics, Institute for Metrology and Biomedical Engineering, Warsaw University of Technology, ul. św. Andrzeja Boboli 8, 02-525, Warsaw, Poland.
Cyrill BurgerPmod Technologies LLC, Sumatrastrasse 25, 8006, Zurich, Switzerland.
Alessandro PasseriNuclear Medicine, ECBSD, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Selene MargiacchiNuclear Medicine, ECBSD, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Paola SalettiMedical Physics, AOU Careggi, Largo Brambilla 3, 50134, Florence, Italy.
Rita BoniniNuclear Medicine, ASL Nord Ovest, Via Risorgimento 18, 54100, Massa, Italy.
Elena LorenziniMedical Physics, ASL Nord Ovest, Piazza Sacco e Vanzetti 5, 54033, Carrara, Italy.
Roberto SciagràNuclear Medicine, ECBSD, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
University of Florence · ITWarsaw University of Technology · PLAzienda Ospedaliero-Universitaria Careggi · IT

Funding

Instytut Metrologii i Inżynierii Biomedycznej, Politechnika Warszawska (PL) Statutory funds
6 · The paper itself

Abstract

objectiveThe aim of this study was to propose and verify a universal method of left ventricular myocardium segmentation, able to operate on heart gated PET data with different sizes, shapes and uptake distributions. The proposed method can be classified as active model method and is based on the BEAS (B-spline Explicit Active Surface) algorithm published by Barbosa et al. The method was implemented within the Pmod PCARD software package. Method verification by comparison with reference software and phantom data is also presented in the paper.

methodsThe proposed method extends the BEAS model by defining mechanical features of the model: tensile strength and bending resistance. Formulas describing model internal energy increase during its stretching and bending are proposed. The segmentation model was applied to the data of 60 patients, who had undergone cardiac gated PET scanning. QGS by Cedars-Sinai and ECTb by Emory University Medical Centre served as reference software for comparing ventricular volumes. The method was also verified using data of left ventricular phantoms of known volume.

resultsThe results of the proposed method are well correlated with the results of QGS (slope: 0.841, intercept: 0.944 ml, R

conclusionsThe analysis of gated PET data by the proposed method results in volume measurements comparable to established methods. Phantom experiments demonstrate that the volume values correspond to the physical ones.

Indexed as

Cardiac-Gated Imaging TechniquesMyocardiumPositron-Emission TomographyAlgorithmsBiomechanical PhenomenaHeart VentriclesHumansImaging, Three-DimensionalPhantoms, ImagingSoftwareTensile StrengthGated PET imagingSegmentation methodVolume quantification, left ventricle, cardiology

Identifiers

PMID31154573
PMCPMC6660505
OpenAlexW2947965058

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.