Evidence map›Paper›PMID 31154569›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2019

Selective and Apoptotic Action of Ethanol Extract of Annona cherimola Seeds against Human Stomach Gastric Adenocarcinoma Cell Line AGS.

Johan Macuer-Guzmán, Giuliano Bernal, Fabiola Jamett-Díaz, Sebastian Ramírez-Rivera, Cristian Ibáñez

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Molecules (Basel, Switzerland) · 2023
    Article
  4. Anticancer acumens of three Annona species: a proportional review.Journal of cancer research and clinical oncology · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Johan Macuer-GuzmánLaboratorio de Silvogenómica y Biotecnología, Departamento de Biología, Facultad de Ciencias Universidad de La Serena, Avenida Raúl Bitrán 1305, Casilla 599, 1700000, La Serena, Chile.
Giuliano BernalLaboratorio de Biología Molecular y Celular del Cáncer, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Larrondo 1281, 1781421, Coquimbo, Chile.
Fabiola Jamett-DíazLaboratorio de Fitoquímica y Productos Naturales, Departamento de Química, Facultad de Ciencias, Universidad de La Serena, Avenida Raúl Bitrán 1305, Casilla 599, 1700000, La Serena, Chile.
Sebastian Ramírez-RiveraLaboratorio de Biología Molecular y Celular del Cáncer, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Larrondo 1281, 1781421, Coquimbo, Chile.
Cristian IbáñezLaboratorio de Silvogenómica y Biotecnología, Departamento de Biología, Facultad de Ciencias Universidad de La Serena, Avenida Raúl Bitrán 1305, Casilla 599, 1700000, La Serena, Chile. cibanez@userena.cl.ORCID http://orcid.org/0000-0001-7767-6488
University of La Serena · CLUniversidad Católica del Norte · CL

Funding

CORFO 14IDL2-30087DIDULS PR90/2014Universidad de La Serena PR13161
6 · The paper itself

Abstract

Annona cherimola is a tree belonging to the family Annonacea, whose fruit (cherimoya) is very desirable, but its seeds are considered waste. Present in these seeds are compounds that have been described as selective antiproliferative agents for cancer cells. The aim of this study was to evaluate the antiproliferative activity of ethanol macerate extract (EMCHS) obtained from A. cherimola seeds against the human stomach gastric adenocarcinoma (AGS) cell line and the normal human gastric epithelial cell line (GES-1). The EMCHS extract presented an IC

Indexed as

AdenocarcinomaAnnonaApoptosisApoptosis Regulatory ProteinsCell LineCell Line, TumorCell ProliferationEpithelial CellsEthanolGene ExpressionHumansPlant ExtractsProto-Oncogene ProteinsSeedsStomachStomach NeoplasmsApoptosis Regulatory ProteinsBBC3 protein, humanEthanolPlant ExtractsProto-Oncogene ProteinsAnnona cherimolaApoptosisEthanolic extractGastric cancerPUMA

Identifiers

PMID31154569
OpenAlexW2947712366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.