Evidence map›Paper›PMID 31154494›Full record

ArticleSkeletal radiology2019

Is fat suppression in T1 and T2 FSE with mDixon superior to the frequency selection-based SPAIR technique in musculoskeletal tumor imaging?

Willemijn H F Huijgen, Catherina S P van Rijswijk, Johan L Bloem

Abstract read
In one paragraph

Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Willemijn H F HuijgenLeiden University Medical Centre (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. willemijnhuijgen@gmail.com.ORCID http://orcid.org/0000-0001-7711-0636
Catherina S P van RijswijkLeiden University Medical Centre (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Johan L BloemLeiden University Medical Centre (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the image quality of fast spin echo (FSE) with mDixon relative to spectral attenuated inversion recovery (SPAIR) FSE sequences in musculoskeletal tumor imaging on a 1.5-T MRI system. MATERIALS AND

methodsIn a HIPAA-compliant prospective study, 265 patients requiring musculoskeletal tumor MRI scans were included. Patient consent was waived by the medical ethical committee. Two radiologists compared SPAIR and mDixon FSE water-only images in both T2- and T1-weighted gadolinium-enhanced (T1-Gd) sequences using a five-point scale (paired samples t test and visual grading characteristics curves (VGC)). Homogeneity of fat suppression, noise, contrast, several artifacts (motion, phase, edge blurring and water-fat swap) and subjective preference were evaluated.

resultsReaders did not have subjective preference for either sequence in 71% and 55% (reader 1 and 2, respectively). Scores for homogeneous fat suppression were significantly (p < 0.01) higher for mDixon (4.88 in T2 and 4.87 in T1-Gd) than for SPAIR (4.31 for T2 and 4.21 for T1-Gd). All VGC curves for homogeneity demonstrated preference for mDixon. In 57 individual mDixon cases, fat-suppression homogeneity was strikingly better (≥ 2 points higher), namely in areas with field heterogeneity. Average noise and contrast scores were slightly higher for mDixon, as were motion artifact scores for SPAIR (< 0.5 points difference).

conclusionsmDixon fat suppression was significantly more homogeneous than SPAIR on both T2 and T1-Gd FSE images in musculoskeletal tumor protocols. In areas of field inhomogeneity, mDixon outperforms SPAIR. SPAIR had slightly less motion artifacts than mDixon.

Indexed as

Adipose TissueAdolescentAdultAgedAged, 80 and overArtifactsBone NeoplasmsChildContrast MediaFemaleHumansImage EnhancementMagnetic Resonance ImagingMaleMeglumineMiddle AgedContrast Mediagadoterate meglumineMeglumineOrganometallic CompoundsDixonFat suppressionHomogeneityImage qualityMagnetic resonance imagingSPAIR

Identifiers

PMID31154494
PMCPMC6813285

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.