Evidence map›Paper›PMID 31154395›Full record

GuidelineGut2019

British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis.

Michael Huw Chapman, Douglas Thorburn, Gideon M Hirschfield, George G J Webster, Simon M Rushbrook, Graeme Alexander, Jane Collier, Jessica K Dyson, David Ej Jones, Imran Patanwala and 3 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Gut, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 8 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 8 syntheses or guidelines pooled it, 277 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. [Guidelines on the diagnosis and management of primary sclerosing cholangitis (2021)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Guideline
  7. Pooled it
  8. Pooled it
  9. Dietary Habits of Individuals With Primary Sclerosing Cholangitis-Poor Fat-Soluble Vitamin Intake and Dietary Quality.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Trial
  10. PSC-DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  11. Article
  12. Fatigue and Cognitive Impairment in Adults With Primary Sclerosing Cholangitis: Results From Concept Elicitation Interviews.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Michael Huw ChapmanGI Division, UCL Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0002-5165-9708
Douglas ThorburnLiver Unit, Royal Free London NHS Foundation Trust, London, UK.
Gideon M HirschfieldToronto Centre for Liver Disease, University Health Network and University of Toronto, Toronto, Canada.
George G J WebsterGI Division, UCL Hospitals NHS Foundation Trust, London, UK.
Simon M RushbrookDepartment of Hepatology, Norfolk and Norwich University Hospitals NHS Trust, Norwich, UK.
Graeme AlexanderLiver Unit, Royal Free London NHS Foundation Trust, London, UK.
Jane CollierHepatology, John Radcliffe Hospital, Oxford, UK.
Jessica K DysonHepatology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.
David Ej JonesInstitute of Cellular Medicine, Newcastle University, Newcastle, UK.
Imran PatanwalaGastroenterology, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
Collette ThainPBC Foundation, Edinburgh, UK.
Martine WalmsleyChair of Trustees PSC Support, Didcot, UK.
Stephen P PereiraGI Division, UCL Hospitals NHS Foundation Trust, London, UK.
University College London Hospitals NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBJohn Radcliffe Hospital · GBNewcastle University · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBNorfolk and Norwich University Hospitals NHS Foundation Trust · GBPBC Foundation · GBUniversity Health Network · CAUniversity of Liverpool · GB

Funding

Department of Health
6 · The paper itself

Abstract

These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included medical representatives from hepatology and gastroenterology groups as well as patient representatives from PSC Support. The guidelines aim to support general physicians, gastroenterologists and surgeons in managing adults with PSC or those presenting with similar cholangiopathies which may mimic PSC, such as IgG4 sclerosing cholangitis. It also acts as a reference for patients with PSC to help them understand their own management. Quality of evidence is presented using the AGREE II format. Guidance is meant to be used as a reference rather than for rigid protocol-based care as we understand that management of patients often requires individual patient-centred considerations.

Indexed as

Biliary Tract NeoplasmsCholangitis, SclerosingDiagnostic Techniques, Digestive SystemDiagnosis, DifferentialHumansImmunoglobulin G4-Related DiseasePatient Care ManagementPrognosisUnited Kingdomsclerosing cholangitis

Identifiers

PMID31154395
PMCPMC6691863
OpenAlexW2947046480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.