Evidence map›Paper›PMID 31154346›Full record

ArticleBMJ case reports2019

Successful treatment of a

Andrew H Zureick, Kathryn A McFadden, Rajen Mody, Carl Koschmann

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Distinct Driver Pathway Enrichments and a High Prevalence ofInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Autophagy as a Potential Therapy for Malignant Glioma.Pharmaceuticals (Basel, Switzerland) · 2020
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew H ZureickUniversity of Michigan Medical School, Michigan Medicine, Ann Arbor, Michigan, USA.
Kathryn A McFaddenDepartment of Pathology, Michigan Medicine, Ann Arbor, Michigan, USA.
Rajen ModyDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Michigan Medicine, Ann Arbor, Michigan, USA.
Carl KoschmannDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Michigan Medicine, Ann Arbor, Michigan, USA.ORCID http://orcid.org/0000-0002-0825-7615
Michigan Medicine · USBeaumont Health · US

Funding

Sequencing, Analysis, and Interpretation of SequencingUM1HG006508 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PIENTA, KENNETH J., ROBERTS, SCOTT · 2013 to 2016
$7.8M
Targeting ATRX-Deficient Pediatric GBMK08NS099427 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOSCHMANN, CARL J · 2017 to 2021
$811k
NHGRI NIH HHS UM1 HG006508NINDS NIH HHS K08 NS099427
6 · The paper itself

Abstract

A 14-year-old boy with familial Li-Fraumeni syndrome presented with diplopia. Brain MRI revealed a right temporoparietal rim-enhancing mass. Following surgical resection and diagnosis of a gigantocellular-type glioblastoma multiforme (GBM), his family wished to avoid cytotoxic chemotherapy given the amplified risk of secondary malignancy. As such, we performed whole exome and transcriptome sequencing, which revealed germline

Indexed as

Li-Fraumeni SyndromeAdolescentBrain NeoplasmsCombined Modality TherapyDiagnosis, DifferentialDiplopiaEverolimusGlioblastomaHumansImmunosuppressive AgentsMaleParietal LobePrecision MedicineTemporal LobeTuberous Sclerosis Complex 2 ProteinEverolimusImmunosuppressive AgentsTSC2 protein, humanTuberous Sclerosis Complex 2 Proteincancer interventionCNS cancerneuro-oncologypaediatric oncology

Identifiers

PMID31154346
PMCPMC6557420
OpenAlexW2947824260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.