Evidence map›Paper›PMID 31154014›Full record

ReviewAgeing research reviews2019

Effects of light on aging and longevity.

Jie Shen, John Tower

Open access · greenAbstract readReview
In one paragraph

Review in Ageing research reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Effects of Light on Vertebrate Welfare: A Review.Animals : an open access journal from MDPI · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Blue light-induced lipid oxidation and the antioxidant property of hypotaurine: evaluation via measuring ultraweak photon emission.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jie ShenCollege of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, Hangzhou, 310018, China. Electronic address: shenjie@hdu.edu.cn.
John TowerMolecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles CA 90089-2910, United States.
Hangzhou Dianzi University · CNUniversity of Southern California · US

Funding

Sex-Specific Aging MechanismsR01AG057741 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOWER, JOHN GERARD · 2018 to 2021
$1.5M
NIA NIH HHS R01 AG057741
6 · The paper itself

Abstract

Increasing evidence suggests an important role for light in regulation of aging and longevity. UV radiation is a mutagen that can promote aging and decrease longevity. In contrast, NIR light has shown protective effects in animal disease models. In invertebrates, visible light can shorten or extend lifespan, depending on the intensity and wavelength composition. Visible light also impacts human health, including retina function, sleep, cancer and psychiatric disorders. Possible mechanisms of visible light include: controlling circadian rhythms, inducing oxidative stress, and acting through the retina to affect neuronal circuits and systems. Changes in artificial lighting (e.g., LEDs) may have implications for human health. It will be important to further explore the mechanisms of how light affects aging and longevity, and how light affects human health.

Indexed as

AgingCircadian RhythmLightLongevitySleepAnimalsHumansOxidative StressPhototherapyRetinaAgingCircadian rhythmsLightMitochondriaOxidative stressPhototherapy

Identifiers

PMID31154014
PMCPMC6663583
OpenAlexW2947813277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.