Evidence map›Paper›PMID 31153968›Full record

ArticleAntiviral research2019

Heterologous prime-boost immunization with vesiculovirus-based vectors expressing HBV Core antigen induces CD8

Carolina Chiale, Safiehkhatoon Moshkani, John K Rose, Michael D Robek

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antiviral research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carolina ChialeDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Safiehkhatoon MoshkaniDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
John K RoseDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA.
Michael D RobekDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA. Electronic address: robekm@amc.edu.
Albany Medical Center Hospital · USYale University · US

Funding

Highly Attenuated Vesiculovirus-based Vectors as HBV Therapeutic VaccinesR01AI124006 · NIAID · ALBANY MEDICAL COLLEGE · PI ROBEK, MICHAEL · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI124006
6 · The paper itself

Abstract

Chronic hepatitis B virus (HBV) infections cause more than 800,000 deaths per year and currently approved treatments do not cure the disease. Because a hallmark of acute infection resolution is the presence of functional CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesGenetic VectorsHepatitis BHepatitis B Core AntigensHepatitis B VaccinesHepatitis B virusImmunization, SecondaryLiverMaleMiceMice, Inbred C57BLSemliki forest virusVaccinationVaccines, AttenuatedVaccines, Virus-Like ParticleHepatitis B Core AntigensHepatitis B VaccinesVaccines, AttenuatedVaccines, Virus-Like ParticleAAVCore antigenHBVPrime-boostVirus-based vectorsVSV

Identifiers

PMID31153968
PMCPMC6660017
OpenAlexW2947951885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.