ReviewPhysiology & behavior2019
Examining weight suppression as a transdiagnostic factor influencing illness trajectory in bulimic eating disorders.
Review in Physiology & behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Examining weight suppression as a predictor and moderator of intervention outcomes in an eating disorder and obesity prevention trial: A replication and extension study.Behaviour research and therapy · 2021Trial
- Weight Suppression, Brain Reward Response to Food Cues, and Bulimic Behaviours: A Pilot fMRI Study.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Bulimia nervosa.Nature reviews. Disease primers · 2026Review
- Adult users of a digital binge-eating intervention wanted adaptations for type 2 diabetes: Qualitative study of post-intervention preferences.Research square · 2026Article
- Beyond weight loss: Integrating GLP-1 RA therapies into psychological and behavioral care for obesity and binge eating disorder.Reviews in endocrine & metabolic disorders · 2026Review
- Weight Suppression and Risk for Childhood Psychiatric Disorders.Child psychiatry and human development · 2025Article
- Test of a biobehavioral model linking weight suppression to binge-eating severity via leptin and glucagon-like peptide 1 in bulimia nervosa and related syndromes in women.Psychological medicine · 2025Article
- Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study.JMIR research protocols · 2025Article
- The association between cumulative adverse childhood experiences and ultra-processed food addiction is moderated by substance use disorder history among adults seeking outpatient nutrition counseling.Frontiers in psychiatry · 2025Article
- Understanding Bone Density Loss in Eating Disorders: Contributions of Weight Suppression and Speed of Weight Loss.Journal of clinical medicine · 2024Article
- Elevated interleukin-6 in women with binge-eating spectrum disorders.The International journal of eating disorders · 2024Article
- A novel weight suppression score associates with distinct eating disorder and ultra-processed food symptoms compared to the traditional weight suppression measure among adults seeking outpatient nutrition counseling.Journal of eating disorders · 2024Article
- Predictors of Treatment Outcome in Eating Disorders: A Roadmap to Inform Future Research Efforts.Current psychiatry reports · 2023Review
- Examining the role of urgency in predicting binge size in bulimia nervosa.Frontiers in psychology · 2023Article
- Patient-Centered Care for Obesity: How Health Care Providers Can Treat Obesity While Actively Addressing Weight Stigma and Eating Disorder Risk.Journal of the Academy of Nutrition and Dietetics · 2022Article
- Reliability and validity of a transdiagnostic measure of reward valuation effort.Psychological assessment · 2022Article
- Associations among weight suppression, self-acceptance, negative body image, and eating disorder behaviors among women with eating disorder symptoms.Women & health · 2021Article
- Exploring Correlates of Loss of Control Eating in a Nonclinical Sample.Frontiers in psychology · 2021Article
- The role of sexual assault history and PTSD in responses to food intake among women with bulimic-spectrum eating disorders.Eating disordersArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Recent research indicates that weight suppression (WS: defined as the difference between highest lifetime and current weight) prospectively predicts illness trajectory across eating disorders characterized by binge eating, including AN binge-purge subtype (ANbp), bulimia nervosa (BN), and binge eating disorder (BED), collectively referred to as bulimic eating disorders. Through a series of studies, we have developed a model to explain the link between WS and illness trajectory in bulimic eating disorders. Our model posits that WS contributes to reduced circulating leptin, which leads to reduced postprandial glucagon-like peptide 1 (GLP-1) response. Diminished leptin and GLP-1 function contribute to alterations in two reward-related constructs in the Research Domain Criteria (RDoC): reward value/effort and reward satiation. Respectively, these changes increase drive/motivation to consume food and decrease ability for food consumption to lead to a state of satiation/satisfaction. Combined, these alterations increase risk for experiencing large, out-of-control binge-eating episodes. The following review presents evidence that contributed to the development of this model as well as preliminary findings from an on-going project funded to test this model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.