Evidence map›Paper›PMID 31153362›Full record

ArticleBMC musculoskeletal disorders2019

A randomised controlled trial of multimodal physiotherapy versus advice for recent onset, painful cervical radiculopathy - the PACeR trial protocol.

Louise Keating, Caroline Treanor, Julie Sugrue, Dara Meldrum, Ciaran Bolger, Catherine Doody

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02449200 (A Randomised Controlled Trial of Multimodal Physiotherapy for Patients With Acute / Sub-acute Cervical Radiculopathy), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02449200 naunknown statusnot on this map

A Randomised Controlled Trial of Multimodal Physiotherapy for Patients With Acute / Sub-acute Cervical Radiculopathy

TypeinterventionalSponsorRoyal College of Surgeons, IrelandRan2015 to 2019Enrolled64ConditionsCervical RadiculopathyArmsMultimodal physiotherapy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Telerehabilitation for neck pain.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Louise KeatingSchool of Physiotherapy, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland. lkeating@rcsi.ie.ORCID http://orcid.org/0000-0003-4747-0491
Caroline TreanorDepartment of Physiotherapy, Beaumont Hospital, Dublin, Ireland.
Julie SugrueDepartment of Physiotherapy, Beaumont Hospital, Dublin, Ireland.
Dara MeldrumSchool of Medicine, Trinity College, Dublin, Ireland.
Ciaran BolgerDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Catherine DoodySchool of Public Health, Physiotherapy & Population Science, University College, Dublin, Ireland.
Beaumont Hospital · IERoyal College of Surgeons in Ireland · IETrinity College Dublin · IEUniversity College Dublin · IE

Funding

EUROSPINE EUROSPINE TFR 9---2014Irish Society Of Chartered Physiotherapists N/A
6 · The paper itself

Abstract

backgroundA research gap exists for optimal management of cervical radiculopathy in the first 12 weeks and short term natural history of the condition is somewhat unclear, although thought to be favourable. The primary aim of this assessor blinded, superiority, 2 parallel group randomised controlled trial is to investigate the effects of a 4 week physiotherapy programme (6-8 sessions) of manual therapy, exercise and upper limb neural unloading tape, compared to a control of weekly phone advice; on disability, pain and selected biopsychosocial measures, in acute and sub-acute cervical radiculopathy patients. A secondary aim is to identify whether any baseline variables, symptom duration or group allocation can predict outcome.

methodsParticipants are recruited from GP referrals in an urban setting, from a neurosurgery non-urgent waiting list and from self-referral through Facebook advertising. Eligible participants (n = 64) are diagnosed with radiculopathy based on a clinical prediction rule and must have symptoms of unilateral, single level, radiculopathy for between 2 and 12 weeks, without having yet received physiotherapy. Random 1:1 group allocation (using variable block sizes), allocation concealment, blinded assessment and intention to treat analysis are being employed. Treatment is provided by clinical specialist physiotherapists in primary and secondary care settings. Outcomes are measured at baseline, 4 (primary endpoint) and 12 weeks. Participants' report of pain, disability and their rating of recovery is also recorded by telephone interview at 6 months. Statistical analysis of between group differences will be performed with ANOVAs and MANOVAs, and multivariable regression analysis will be undertaken to explore predictor variables. Ethical approval for this study has been received from the Beaumont Hospital and Irish College of General Practitioners Research Ethics Committees. The trial is registered at ClinicalTrials.gov (NCT02449200). DISCUSSION: An internal pilot study to test retention and recruitment strategies led to trial expansion and this is now a multi centre trial involving 5 clinical sites.

trial registrationNCT02449200 . Registered 20/05/15.

Indexed as

AdultAthletic TapeCervical VertebraeCombined Modality TherapyConservative TreatmentEquivalence Trials as TopicExercise TherapyFemaleHumansMaleMulticenter Studies as TopicMusculoskeletal ManipulationsNeck PainPain MeasurementPilot ProjectsQuality of LifeCervical radiculopathyExerciseManual therapyPhysiotherapyPressure algometryUnloading tape

Identifiers

PMID31153362
PMCPMC6545204
OpenAlexW2947832572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.