ArticleJournal of affective disorders2019
Social anxiety, posterior insula activation, and autonomic response during self-initiated action in a Cyberball game.
Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Upward and downward comparisons across monetary and status domains.Human brain mapping · 2020Pooled it
- Research Domain Criteria (RDoC) Constructs of Acute and Potential Threat Differentially Associate With Pediatric Anxiety.JAACAP open · 2025Article
- Article
- Individual Differences in Bodily Self-Consciousness and Its Neural Basis.Brain sciences · 2024Review
- Systematic literature review of human studies assessing the efficacy of cannabidiol for social anxiety.Psychiatry research communications · 2022Article
- Aberrant functional connectivity in insular subregions in somatic depression: a resting-state fMRI study.BMC psychiatry · 2022Article
- Perceived friendship and binge drinking in young adults: A study of the Human Connectome Project data.Drug and alcohol dependence · 2021Article
- Human Responses to Visually Evoked Threat.Current biology : CB · 2021Article
- Perceived burdensomeness and neural responses to ostracism in the Cyberball task.Journal of psychiatric research · 2020Article
- The effects of age on cerebral responses to self-initiated actions during social interactions: An exploratory study.Behavioural brain research · 2020Article
- Interoceptive active inference and self-representation in social anxiety disorder (SAD): exploring the neurocognitive traits of the SAD self.Neuroscience of consciousness · 2020Review
- Review of EEG, ERP, and Brain Connectivity Estimators as Predictive Biomarkers of Social Anxiety Disorder.Frontiers in psychology · 2020Review
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Authors and funding
6 authors.
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Abstract
backgroundAn earlier study characterized the neural correlates of self-initiated actions in a Cyberball game in healthy individuals. It remains unclear how social anxiety may influence these neural processes.
methodsWe examined regional activations to self-initiated actions in 25 adults with low and 25 with high social anxiety (LA and HA, respectively). Skin conductance was recorded concurrently with fMRI. We followed published routines in the analyses of imaging and skin conductance data.
resultsWe hypothesized that HA as compared to LA individuals would demonstrate increased cortical limbic activations during self-initiated actions (tossing or T > receiving or R trials, to control for motor activities) in social exclusion (EX) vs. fair game (FG) scenario. At a corrected threshold, HA as compared with LA group showed increases in bilateral posterior insula activation during T vs. R trials in EX as compared to FG. Further, HA as compared to LA showed higher skin conductance response to tossing trials during EX as compared to FG. LIMITATIONS: With a limited sample size, we did not examine potential sex effects. Further, we cannot rule out the effects of depression on the findings.
conclusionsTogether, the results suggest that individuals with more severe social anxiety engaged the somatosensory insula to a greater extent and exhibited higher physiological arousal when initiating ball toss during social exclusion in the Cyberball game. Posterior insula response to self-initiated action may represent a biomarker of social anxiety. It remains to be investigated whether interventions to decrease physiological arousal may alleviate social anxiety.
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