Evidence map›Paper›PMID 31152468›Full record

ArticleJournal of clinical laboratory analysis2019

Correlations of severity of asthma in children with body mass index, adiponectin and leptin.

Chunli Ma, Yujun Wang, Man Xue

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Regulatory Peptides in Asthma.International journal of molecular sciences · 2021
    Review
  7. Review
  8. Adiponectin and Asthma: Knowns, Unknowns and Controversies.International journal of molecular sciences · 2021
    Review
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Chunli MaDepartment of Pediatrics, Baoji People's Hospital, Baoji, China.
Yujun WangDepartment of Integrated Traditional Chinese and Western Medicine, Children's Hospital Affiliated to Xi'an Jiaotong University (Xi'an Children's Hospital), Xi'an, China.
Man XueDepartment of Pediatrics, Baoji People's Hospital, Baoji, China.ORCID https://orcid.org/0000-0003-3405-5723
Baoji City Central Hospital · CNXi’an Children’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to investigate the correlations of asthma in children with body mass index (BMI), adiponectin, and leptin.

methodsA total of 122 children with asthma in our hospital from January 2017 to February 2018 were randomly selected and divided into control group (normal) and observation group (BMI > 28 kg/m

resultsBody mass index, leptin level, forced vital capacity (FVC), FVC%, and forced expiratory volume in 1s (FEV1)/FVC in observation group were significantly higher than those in control group (P < 0.05), while the adiponectin level, forced expiratory capacity in 1s (FEC1), and FEV1% in observation group were significantly lower than those in control group (P < 0.05). The amount of severe patients in observation group was much larger than that in control group. The severity of disease was positively correlated with BMI and leptin and negatively correlated with adiponectin. BMI, adiponectin, and leptin were identified as risk factors for asthma in children.

conclusionAdiponectin, leptin, and BMI are involved in the pathogenesis of asthma in children, suggesting they might be therapeutic targets for clinical treatment.

Indexed as

Body Mass IndexAdiponectinAdolescentAsthmaCase-Control StudiesChildFemaleForced Expiratory VolumeHumansLeptinLogistic ModelsMaleRespiratory Function TestsVital CapacityAdiponectinADIPOQ protein, humanLEP protein, humanLeptinadiponectinasthmabody mass indexleptin

Identifiers

PMID31152468
PMCPMC6642295
OpenAlexW2947379311

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.