ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020
Risk of Chronic Opioid Use in Opioid-Naïve and Non-Naïve Patients after Ambulatory Surgery.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- The Effectiveness of the Safety Communication for Concurrent Benzodiazepine-Opioid Therapy: A Retrospective Real-World Analysis.Drugs - real world outcomes · 2026Article
- The impact of opioid prescribing guidelines on opioid dispensation: A systematic review and meta-analysis.Canadian journal of pain = Revue canadienne de la douleur · 2026Review
- Opioid use patterns and persistent use after hemodialysis access surgery.Journal of vascular surgery · 2025Article
- Enhanced Recovery after Surgery Protocol Decreases Length of Stay and Postoperative Narcotic Use in Tissue Expander-based Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2024Article
- Impact of Gabapentin on Postoperative Hypotension in Enhanced Recovery after Surgery Protocols for Microvascular Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2024Article
- Enhanced Recovery after Surgery Protocol Decreases Length of Stay and Postoperative Narcotic Use in Microvascular Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2023Article
- Risk factors for opioid use disorder after severe burns in adults.American journal of surgery · 2023Article
- Opioid prescribing practices and patient-requested refill patterns following laparoscopic inguinal hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Surgeon Bias in Postoperative Opioid Prescribing.World journal of surgery · 2022Article
- Prolonged Opioid Use following Hand Surgery: A Systematic Review and Proposed Criteria.Plastic and reconstructive surgery. Global open · 2022Article
- Multimodal Analgesia After Colorectal Surgery: Quantifying the Decrease in Opioid Consumption.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- A national evaluation of opioid prescribing and persistent use after ambulatory anorectal surgery.Surgery · 2021Article
- Health(care) in the Crisis: Reflections in Science and Society on Opioid Addiction.International journal of environmental research and public health · 2021Review
- Perioperative Multimodal Analgesia Reduces Opioid Use Following Skin Grafting in Nonintubated Burn Patients.Journal of burn care & research : official publication of the American Burn Association · 2020Article
- Opioid use and abuse following video-assisted thoracic surgery (VATS) or thoracotomy lung cancer surgery.Translational lung cancer research · 2019Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic postoperative opioid use has been demonstrated after surgery, but there is a paucity of data on whether the amount of opioids given at discharge is a significant contributor to the risk of prolonged use. The purpose of this study was to determine if higher amounts of opioids prescribed after ambulatory surgery increases chronic opioid use in opioid-naïve and non-naïve patients.
methodsUsing the Institutional Data Warehouse, 15,220 adult patients were identified who underwent ambulatory elective surgeries at our institution between January 2014 and July 2018 and received a perioperative opioid prescription. Multivariate logistic regression was used to characterize the relationship between amount of perioperative opioids prescribed and chronic opioid use.
resultsThe study population consisted of 14,378 (94%) opioid-naïve and 842 (6%) non-naïve patients. Seven hundred fifty-seven (5%) patients received a new opioid prescription 90 to 365 days after surgery. Patients that had a lower amount of total perioperative opioids (0-150MMEs, 151-300MMEs, or 301-450MMEs) had 44-54% lower risk of persistent opioid use after surgery compared to those who received > 450 MMEs or > 60 pills of 5 mg oxycodone (p < 0.0001). This relationship was especially prominent on subset analysis of opioid non-naïve patients, a group that has thus far been left out of opioid-related studies.
conclusionPersistent opioid use is a known complication after surgery. A higher number of opioid pills on discharge after ambulatory surgery is associated with increased risk of chronic opioid use. Surgeons should consider limiting the number of opioid pills prescribed after ambulatory surgery for both opioid-naïve and non-naïve patients.
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