ReviewPain medicine (Malden, Mass.)2019
Burst Spinal Cord Stimulation: A Clinical Review.
Review in Pain medicine (Malden, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- STIMFIX™ anchoring in percutaneous spinal cord stimulation trials: interim analysis of a multicenter study.Pain management · 2025Trial
- Noninvasive neuromodulation reduces symptoms of restless legs syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Trial
- Burst deep brain stimulation for Parkinson's disease: A systematic review of efficacy and safety.Journal of Parkinson's disease · 2026Review
- High-Frequency Spinal Cord Stimulation Modifies Tibial Nerve-Stimulation-Evoked Cortical Theta-Gamma Coupling in Sheep Cortex.The European journal of neuroscience · 2026Article
- Closed-loop SCS and sensing: now and in the future.Pain medicine (Malden, Mass.) · 2026Review
- Effectiveness of Spinal Cord Stimulation in the Treatment of Lumbar Spine Pain Syndromes.Medicina (Kaunas, Lithuania) · 2026Article
- Spinal Cord Stimulation: Mechanisms of Action, Indications, Types, Complications.Journal of clinical medicine · 2025Review
- Role of frequency-dependent and capacitive tissue properties in spinal cord stimulation models.Journal of neural engineering · 2025Article
- Neurosurgical Interventions in Chronic Pain Management: A Review of Emerging Technologies and Accessibility.Current pain and headache reports · 2025Review
- A comprehensive review of the supraspinal mechanisms of spinal cord stimulation on chronic pain and cognition.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- BurstDR™ spinal cord stimulation for chemotherapy-induced peripheral neuropathy.Surgical neurology international · 2025Article
- Spinal Cord Stimulation Waveforms for the Treatment of Chronic Pain.Current pain and headache reports · 2024Review
- Neuromodulation and Habituation: A Literature Review and Conceptional Analysis of Sustaining Therapeutic Efficacy and Mitigating Habituation.Biomedicines · 2024Review
- Artificial Intelligence and Pain Medicine: An Introduction.Journal of pain research · 2024Review
- A Brief Review on the Novel Therapies for Painful Diabetic Neuropathy.Current pain and headache reports · 2023Review
- Objective wearable measures correlate with self-reported chronic pain levels in people with spinal cord stimulation systems.NPJ digital medicine · 2023Article
- Advances in Spinal Cord Stimulation.Bioengineering (Basel, Switzerland) · 2023Review
- Neuromodulation for functional upper gastrointestinal diseases.Gut microbiota and integrative wellness · 2023Article
- Article
- Burst Spinal Cord Stimulation in the Management of Chronic Pain: Current Perspectives.Anesthesiology and pain medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveClinical review on outcomes using burst spinal cord stimulation (SCS) in the treatment of chronic, intractable pain.
designNarrative clinical literature review conducted utilizing a priori search terms including key words for burst spinal cord stimulation. Synthesis and reporting of data from publications including an overview of comparative SCS outcomes.
resultsBurst SCS demonstrated greater pain relief over tonic stimulation in multiple studies, which included blinded, sham-controlled, randomized trials. Additionally, burst stimulation impacts multiple dimensions of pain, including somatic pain as well as emotional and psychological elements. Patient preference is weighted toward burst over tonic due to increased pain relief, a lack of paresthesias, and impression of change in condition.
conclusionBurst SCS has been shown to be both statistically and clinically superior to tonic stimulation and may provide additional benefits through different mechanisms of action. Further high-quality controlled studies are warranted to not only elucidate the basic mechanisms of burst SCS but also address how this unique stimulation signature/pattern may more adequately handle the multiple affective dimensions of pain in varying patient populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.