Evidence map›Paper›PMID 31152082›Full record

ArticleThe oncologist2019

Safety and Success of Repeat Lung Needle Biopsies in Patients with Epidermal Growth Factor Receptor-Mutant Lung Cancer.

Florian J Fintelmann, Fabian M Troschel, Martin W Kuklinski, Shaunagh McDermott, Milena Petranovic, Subba R Digumarthy, Amita Sharma, Amelie S Troschel, Melissa C Price, Lida P Hariri and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in The oncologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Florian J FintelmannDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA fintelmann@mgh.harvard.edu.ORCID 0000-0002-0119-3903
Fabian M TroschelDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Martin W KuklinskiDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Shaunagh McDermottDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Milena PetranovicDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Subba R DigumarthyDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Amita SharmaDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Amelie S TroschelDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-2727-7160
Melissa C PriceDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Lida P HaririDepartment of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Matthew D GilmanDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Joanne O ShepardDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts, USA.
Lecia V SequistMassachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Zofia PiotrowskaMassachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Massachusetts General Hospital · US

Funding

The Activation of ERBB3 Signaling as a Resistance Mechanism to Targeted TherapiesR01CA137008 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Aaron N Hata, ZOFIA PIOTROWSKA · 2009 to 2026
$5.7M
NCI NIH HHS R01 CA137008
6 · The paper itself

Abstract

backgroundPostprogression repeat biopsies are critical in caring for patients with lung cancer with epidermal growth factor receptor ( MATERIALS AND

methodsAll lung biopsies performed at our hospital from 2009 to 2017 were reviewed. Complications were classified by Society of Interventional Radiology criteria. Complication rates between rebiopsies in

resultsDuring the study period, nine thoracic radiologists performed 107 rebiopsies in 75

conclusionAt our center, repeat lung biopsies for postprogression molecular profiling of IMPLICATIONS FOR PRACTICE: Repeat percutaneous transthoracic needle aspirations and biopsies for postprogression molecular profiling of epidermal growth factor receptor (

Indexed as

AgedBiopsy, Fine-NeedleDisease ProgressionErbB ReceptorsFemaleHumansLung NeoplasmsMaleMiddle AgedMolecular Targeted TherapyRetrospective StudiesErbB ReceptorsComplicationsDisease progressionMolecular targeted therapyNeedle biopsyNon‐small cell lung cancer

Identifiers

PMID31152082
PMCPMC6975961
OpenAlexW2947117256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.