Evidence map›Paper›PMID 31151965›Full record

ArticleCancer immunology research2019

HPV Epitope Processing Differences Correlate with ERAP1 Allotype and Extent of CD8

Emma Reeves, Oliver Wood, Christian H Ottensmeier, Emma V King, Gareth J Thomas, Tim Elliott, Edward James

Open access · bronzeAbstract read
In one paragraph

Article in Cancer immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

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  7. Biology of HLA class I associated inflammatory diseases.Best practice & research. Clinical rheumatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Emma ReevesCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.
Oliver WoodCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.
Christian H OttensmeierCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.ORCID 0000-0003-3619-1657
Emma V KingCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.
Gareth J ThomasCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.
Tim ElliottCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.ORCID 0000-0003-1097-0222
Edward JamesCentre for Cancer Immunology, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom. eddjames@soton.ac.uk.ORCID 0000-0001-8638-7928
Southampton General Hospital · GB

Funding

Cancer Research UK 16997Cancer Research UK 21998Cancer Research UK A16997
6 · The paper itself

Abstract

Presence of tumor-infiltrating lymphocytes (TIL) predicts survival in many cancer types. In HPV-driven cancers, cervical and oropharyngeal squamous cell carcinomas (CSCC and OPSCC, respectively), numbers of infiltrating T cells, particularly CD8

Indexed as

AminopeptidasesAntigen PresentationCarcinoma, Squamous CellCD8-Positive T-LymphocytesCohort StudiesEpitopesHumansLymphocytes, Tumor-InfiltratingMinor Histocompatibility AntigensOncogene Proteins, ViralOropharyngeal NeoplasmsPapillomaviridaePapillomavirus InfectionsPeptide FragmentsPolymorphism, GeneticAminopeptidasesEpitopesERAP1 protein, humanMinor Histocompatibility AntigensOncogene Proteins, ViralPeptide Fragments

Identifiers

PMID31151965
PMCPMC6640044
OpenAlexW2947783896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.