Evidence map›Paper›PMID 31151962›Full record

ArticleCancer research2019

Inactivation of

Anna-Mariya Kukuyan, Eleonora Sementino, Yuwaraj Kadariya, Craig W Menges, Mitchell Cheung, Yinfei Tan, Kathy Q Cai, Michael J Slifker, Suraj Peri, Andres J Klein-Szanto and 2 more

Abstract read
In one paragraph

Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Pleural mesothelioma.Nature reviews. Disease primers · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Contemporary management of mesothelioma.Breathe (Sheffield, England) · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anna-Mariya KukuyanCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Eleonora SementinoCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Yuwaraj KadariyaCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Craig W MengesCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Mitchell CheungCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Yinfei TanCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Kathy Q CaiHistopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Michael J SlifkerBioinformatics and Biostatistics Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.ORCID 0000-0002-9718-5966
Suraj PeriBioinformatics and Biostatistics Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Andres J Klein-SzantoHistopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Frank J RauscherWistar Institute, Philadelphia, Pennsylvania.
Joseph R TestaCancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania. joseph.testa@fccc.edu.ORCID 0000-0003-1301-5175
Fox Chase Cancer Center · USThe Wistar Institute · US

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9M
The Role of p21-Activated Kinases in Malignant MesotheliomaR01CA148805 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI CHERNOFF, JONATHAN, TESTA, JOSEPH R. · 2011 to 2020
$4.0M
Pathogenesis of Malignant Mesothelioma by the Human Polycomb Complex BAP1-ASXLR01CA175691 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI RAUSCHER III, FRANK JOSEPH, TESTA, JOSEPH R. · 2014 to 2018
$2.7M
NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA010815NCI NIH HHS R01 CA148805NCI NIH HHS R01 CA175691
6 · The paper itself

Abstract

Pleural malignant mesothelioma is a therapy-resistant cancer affecting the serosal lining of the thoracic cavity. Mutations/deletions of

Indexed as

AnimalsCyclin-Dependent Kinase Inhibitor p16Gene Expression Regulation, NeoplasticLung NeoplasmsMesotheliomaMesothelioma, MalignantMice, KnockoutNeurofibromin 2Pleural NeoplasmsPolycomb Repressive Complex 2Tumor Suppressor ProteinsUbiquitin ThiolesteraseBAP1 protein, mouseCdkn2a protein, mouseCyclin-Dependent Kinase Inhibitor p16Neurofibromin 2Nf2 protein, mousePolycomb Repressive Complex 2Tumor Suppressor ProteinsUbiquitin Thiolesterase

Identifiers

PMID31151962
PMCPMC6697648
OpenAlexW2947324713

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.