ArticleJournal of medical case reports2019
Primary squamous cell carcinoma of the endometrium associated with human papilloma virus in a young woman: a case report.
Article in Journal of medical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Primary endometrial squamous cell carcinoma with molecular Characterization: A case report.Gynecologic oncology reports · 2026Article
- Superficial spreading squamous cell carcinoma of the cervix involving the endometrium: A case report and literature review.Experimental and therapeutic medicine · 2025Article
- Case report: Clinicopathological characteristic of two cases of primary endometrial squamous cell carcinoma and review of the literature.Frontiers in oncology · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary squamous cell carcinoma of the endometrium is an extremely rare tumor with poorly understood pathogenesis. CASE PRESENTATION: We report a case of a 28-year-old Togolese woman who had consulted for vaginal bleeding and pelvic pain. Ultrasound showed thickening of the lining of the endometrium, and biopsy curettage was done. Anatomopathological examination was noteworthy for a proliferation of squamous cells often connected by union bridges arranged in tumor lobules with dyskeratotic maturation. Immunohistochemistry showed epithelial membrane antigen positivity, anti-pancytokeratin 1 markers of tumor cells positivity, chromogranin A negativity, actin negativity, S100 negativity, estrogen receptor negativity, and progesterone receptor negativity. In situ hybridization had objectified human papillomavirus genotypes 16/18. The diagnosis of primary squamous cell carcinoma of the endometrium associated with human papilloma virus was retained. A hysterectomy was performed, and the tumor was classified pT1N0M0.
conclusionThe pathogenesis of this endometrial cancer is complex, and its association with human papillomavirus does not explain its genesis.
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