Evidence map›Paper›PMID 31151427›Full record

ReviewBMC cancer2019

Multidisciplinary approach to rare primary cardiac sarcoma: a case report and review.

Audrone Vaitiekiene, Domas Vaitiekus, Laura Urbonaite, Antanas Jankauskas, Justina Portacenko, Tomas Lapinskas, Rimantas Benetis, Adakrius Siudikas, Audrone Veikutiene, Lina Poskiene and 6 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Audrone VaitiekieneDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania. audrone.vaitiekiene@lsmuni.lt.
Domas VaitiekusDepartment of Oncology and Hematology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Laura UrbonaiteDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Antanas JankauskasDepartment of Radiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Justina PortacenkoDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Tomas LapinskasDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rimantas BenetisDepartment of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Adakrius SiudikasDepartment of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Audrone VeikutieneDepartment of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lina PoskieneDepartment of Pathology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Ausra KavoliunieneDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rasa JanciauskieneDepartment of Oncology and Hematology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Laimonas JaruseviciusDepartment of Oncology and Hematology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Elona JuozaityteDepartment of Oncology and Hematology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Remigijus ZaliunasDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Egle EreminieneDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUndifferentiated pleomorphic sarcoma is a very rare and aggressive type of primary cardiac tumors. Most cardiac sarcomas result in rapid growth and quick death. According to different sources the median survival is typically 6 to 12 months. We are presenting a case of primary cardiac sarcoma with 26 months disease free survival following cytoreductive surgery and chemotherapy. CASE PRESENTATION: A 48-year-old woman with progressing symptoms of dyspnea and palpitations for over 2 months was referred to a cardiologist. With the help of echocardiography and cardiovascular magnetic resonance cardiac sarcoma was suspected. Open biopsy and cytoreductive surgery were performed, complete resection of the tumor was not possible. Histology revealed undifferentiated pleomorphic sarcoma. Seven cycles of chemotherapy with Doxorubicine and Ifosfamide were completed. Cardiovascular magnetic resonance revealed a complete response - only signs of fibrosis without any signs of tumor were visible. Follow ups with echocardiography, cardiovascular magnetic resonance and chest, abdomen and pelvic computed tomography is performed every 3 months. Twenty-six months from initial diagnosis the patient is still free of recurrence of tumor with no compromises of the quality of life.

conclusionStandard chemotherapy together with cytoreductive surgery can have a complete response effect in undifferentiated pleomorphic sarcoma with unusual long-term survival.

Indexed as

BiopsyChemotherapy, AdjuvantCombined Modality TherapyCytoreduction Surgical ProceduresDoxorubicinFemaleFollow-Up StudiesHeart NeoplasmsHistiocytoma, Malignant FibrousHumansIfosfamideMiddle AgedQuality of LifeTreatment OutcomeDoxorubicinIfosfamideCardiac sarcomaCardiovascular magnetic resonanceUndifferentiated pleomorphic sarcoma

Identifiers

PMID31151427
PMCPMC6544955
OpenAlexW2947625308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.