Evidence map›Paper›PMID 31151388›Full record

Observational studyBMC emergency medicine2019

ECG alterations suggestive of hyperkalemia in normokalemic versus hyperkalemic patients.

Csaba Varga, Zsolt Kálmán, Alíz Szakáll, Kata Drubits, Márton Koch, Róbert Bánhegyi, Tibor Oláh, Éva Pozsgai, Norbert Fülöp, József Betlehem

Open access · goldAbstract readComparative StudyObservational Study
In one paragraph

Observational study in BMC emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Hyperkalemia in Severe Burn Injuries: Pathogenesis and Therapeutic Advances.Journal of community hospital internal medicine perspectives · 2026
    Review
  3. AI-based prediction of VONPJ microgravity · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Management of hyperkalemia: Expert consensus from Kuwait - a Modified Delphi Approach.International journal of nephrology and renovascular disease · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. ECG frequency changes in potassium disorders: a narrative review.American journal of cardiovascular disease · 2022
    Review
  15. Observational
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Csaba VargaDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
Zsolt KálmánDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
Alíz SzakállDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
Kata DrubitsDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
Márton KochDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
Róbert BánhegyiDepartment of Oncology, Békés County Kálmán Pándy General Hospital, Semmelweis street 1, Gyula, 5700, Hungary.
Tibor OláhDepartment of Surgery, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
Éva PozsgaiDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary. pozsgay83@yahoo.com.
Norbert FülöpDepartment of Emergency Medicine, Somogy County Kaposi Mór General Hospital, Tallián Gyula street 20-32, Kaposvár, 7400, Hungary.
József BetlehemInstitute of Emergency Care and Pedagogy of Health, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály street 4, Pécs, 7621, Hungary.
Somogy Megyei Kaposi Mór Oktató Kórház · HUUniversity of Pecs · HUBékés Megyei Központi Kórház · HUHungarian National Blood Transfusion Service · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn periarrest situations and during resuscitation it is essential to rule out reversible causes. Hyperkalemia is one of the most common, reversible causes of periarrest situations. Typical electrocardiogram (ECG) alterations may indicate hyperkalemia. The aim of our study was to compare the prevalence of ECG alterations suggestive of hyperkalemia in normokalemic and hyperkalemic patients.

methods170 patients with normal potassium (K

results24% of normokalemic patients and 46% of patients with elevated potassium levels had some kind of ECG alteration suggestive of hyperkalemia. Wide QRS (31.6%), peaked T-waves (18.4%), Ist degree AV-block (18.4%) and bradycardia (18.4%) were the most common and significantly more frequent ECG alterations suggestive of hyperkalemia in severely hyperkalemic patients compared with normokalemic patients (8.2, 4.7, 7.1 and 6.5%, respectively). There was no significant difference between the frequency of ECG alterations suggestive of hyperkalemia in normokalemic and moderately hyperkalemic patients. Upon examining ECG alterations not typically associated with hyperkalemia, we found that prolonged QTc was the only ECG alteration which was significantly more prevalent in both patients with moderate (17.5%) and severe hyperkalemia (21.1%) compared to patients with normokalemia (5.3%).

conclusionsA minority of patients with normal potassium levels may also exhibit ECG alterations considered to be suggestive of hyperkalemia, while more than half of the patients with hyperkalemia do not have ECG alterations suggesting hyperkalemia. These results imply that treatment of hyperkalemia in the prehospital setting should be initiated with caution. Multiple ECG alterations, however, should draw attention to potentially life threatening conditions.

Indexed as

ElectrocardiographyComorbidityFemaleHumansHungaryHyperkalemiaMalePotassiumRetrospective StudiesSensitivity and SpecificityPotassiumECG alterationsHyperkalemiaPeaked T wavePeriarrest situationPrehospital settingWide QRS

Identifiers

PMID31151388
PMCPMC6814982
OpenAlexW2947249106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.