Evidence map›Paper›PMID 31151382›Full record

ArticleThe journal of headache and pain2019

Burden and costs of migraine in a Swedish defined patient population - a questionnaire-based study.

Frida Hjalte, Sara Olofsson, Ulf Persson, Mattias Linde

Open access · goldAbstract read
In one paragraph

Article in The journal of headache and pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 58 citations in OpenAlex.

  1. Migraine in the Corporate Sector: Prevalence, Risk Factors, Job Efficiency Impact, and Management Strategies.Medical science monitor : international medical journal of experimental and clinical research · 2026
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  5. Unveiling the Public Economic Burden of Migraine in Argentina.Journal of health economics and outcomes research · 2025
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  11. Headache in Workers: A Matched Case-Control Study.European journal of investigation in health, psychology and education · 2022
    Article
  12. The remarkably frequent use of EQ-5D in non-economic research.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
    Article
  13. Headache in the Workplace: Analysis of Factors Influencing Headaches in Terms of Productivity and Health.International journal of environmental research and public health · 2022
    Article
  14. Prevalence of Migraine in General Spanish Population; Factors Related and Use of Health Resources.International journal of environmental research and public health · 2021
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Frida HjalteThe Swedish Institute for Health Economics (IHE), Lund, Sweden. fh@ihe.se.ORCID http://orcid.org/0000-0001-9721-2330
Sara OlofssonThe Swedish Institute for Health Economics (IHE), Lund, Sweden.
Ulf PerssonThe Swedish Institute for Health Economics (IHE), Lund, Sweden.
Mattias LindeDepartment of Neuromedicine and Movement Sciences, NTNU Norwegian University of Science and Technology, Trondheim, Norway.
Swedish Institute for Health Economics · SENorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMigraine is a disabling, chronic neurological disease leading to severe headache episodes affecting 13.2% of the Swedish population. Migraine leads to an extensive socio-economic burden in terms of healthcare costs, reduced workforce and quality of life (QoL) but studies of the health-economic consequences in a Swedish context are lacking. The objective of this study is to map the health-economic consequences of migraine in a defined patient population in terms of healthcare consumption, production loss and QoL in Sweden.

methodsThe study is based on data from a web-based survey to members in the Swedish patients' association suffering from migraine. The survey was conducted in May 2018 and included people with migraine aged 18 years or older. The survey included questions on health resource consumption, lost production resulting from migraine-related absenteeism and presenteeism, and QoL as measured by the EuroQol 5 dimensions questionnaire (EQ-5D-5 L) and the Headache Impact Test (HIT-6). The results are presented in yearly costs per patient and losses in quality adjusted life years (QALYs).

resultsThe results are based on answers from 630 individuals with migraine and are presented by number of migraine days per month. The total cost per patient and year increased with the number of migraine days per month (p < 0.001) and varied between approximately €5000 for those with less than 3 migraine days per month and €24,000 per year for those with 21-28 migraine days per month. Production loss represented the main part of the costs, approximately 80%. The average loss in QALYs per year also increased with the monthly number of migraine days (p = 0.023).

conclusionsMigraine leads to significant societal costs and loss of quality of life. There appears to be an unmet need and a potential for both cost savings and QoL benefits connected with a reduction in the number of migraine days.

Indexed as

Cost of IllnessSurveys and QuestionnairesAbsenteeismAdultAgedChronic DiseaseFemaleHealth Care CostsHumansMaleMiddle AgedMigraine DisordersQuality of LifeSwedenCostEQ-5DMigraineQuality of lifeSwedenWork productivity

Identifiers

PMID31151382
PMCPMC6734313
OpenAlexW2947125319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.