Evidence map›Paper›PMID 31151314›Full record

ArticleInternational journal of molecular sciences2019

Role of Hyaluronan in Human Adipogenesis: Evidence from in-Vitro and in-Vivo Studies.

Nicholas Wilson, Robert Steadman, Ilaria Muller, Mohd Draman, D Aled Rees, Peter Taylor, Colin M Dayan, Marian Ludgate, Lei Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nicholas WilsonSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. nickmwilson1@gmail.com.
Robert SteadmanSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. SteadmanR@cardiff.ac.uk.
Ilaria MullerSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. MullerI4@cardiff.ac.uk.ORCID 0000-0003-2926-0722
Mohd DramanFaculty of Medicine, Universiti Sultan Zainal Abidin, Jalan Sultan Mahmud, Kuala Terengganu 20400, Malaysia. DramanYusofMS@cardiff.ac.uk.
D Aled ReesSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. ReesDA@cardiff.ac.uk.ORCID 0000-0002-1165-9092
Peter TaylorSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. TaylorPN@cardiff.ac.uk.
Colin M DayanSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. DayanCM@cardiff.ac.uk.
Marian LudgateSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. Ludgate@cardiff.ac.uk.
Lei ZhangSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. ZhangL14@cf.ac.uk.ORCID 0000-0003-3536-8692
Cardiff University · GBSultan Zainal Abidin University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyaluronan (HA), an extra-cellular matrix glycosaminoglycan, may play a role in mesenchymal stem cell differentiation to fat but results using murine models and cell lines are conflicting. Our previous data, illustrating decreased HA production during human adipogenesis, suggested an inhibitory role. We have investigated the role of HA in adipogenesis and fat accumulation using human primary subcutaneous preadipocyte/fibroblasts (PFs,

Indexed as

AdipogenesisAdipose TissueBody Mass IndexCells, CulturedFibroblastsHumansHyaluronan SynthasesHyaluronic AcidPPAR gammaHyaluronan SynthasesHyaluronic AcidPPAR gamma4-methylumbelliferoneAdipogenesisBMIExtracellular matrixfat accumulationhyaluronanmesenchymal stem cellPPARγ

Identifiers

PMID31151314
PMCPMC6600677
OpenAlexW2947854036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.