Evidence map›Paper›PMID 31151304›Full record

ArticleMolecules (Basel, Switzerland)2019

In Vitro and In Vivo Effectiveness of Carvacrol, Thymol and Linalool against

Mohammad Reza Youssefi, Elham Moghaddas, Mohaddeseh Abouhosseini Tabari, Ali Akbar Moghadamnia, Seyed Mohammad Hosseini, Bibi Razieh Hosseini Farash, Mohammad Amin Ebrahimi, Niki Nabavi Mousavi, Abdolmajid Fata, Filippo Maggi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Oregano essential oilFrontiers in cellular and infection microbiology · 2025
    Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Effect of 3-Carene and the Micellar Formulation onTropical medicine and infectious disease · 2023
    Article
  15. Article
  16. In vitro efficacy of plumbagin and thymol againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  17. Antileishmanial Activity and In Silico Molecular Docking Studies ofTropical medicine and infectious disease · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Mohammad Reza YoussefiDepartment of Veterinary Parasitology, Babol-Branch, Islamic Azad University, Babol 8415683111, Iran. youssefi929@hotmail.com.
Elham MoghaddasDepartment of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad 9177899191, Iran. moghaddase@mums.ac.ir.
Mohaddeseh Abouhosseini TabariFaculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol 46131, Iran. m.abouhosseini@ausmt.ac.ir.
Ali Akbar MoghadamniaDepartment of Pharmacology, Babol University of Medical Sciences, Babol 8415683111, Iran. moghadamnia@gmail.com.ORCID 0000-0003-4108-5816
Seyed Mohammad HosseiniDepartment of Veterinary Pathology, Babol-Branch Islamic Azad University, Babol 8415683111, Iran. dr_hosseini2323@yahoo.com.
Bibi Razieh Hosseini FarashDepartment of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad 9177899191, Iran. HoseiniFR@mums.ac.ir.
Mohammad Amin EbrahimiYoung Researcher and Elite Club, Islamic Azad University, Babol-Branch, Babol 8415683111, Iran. mabrahimi@rocketmail.com.
Niki Nabavi MousaviYoung Researcher and Elite Club, Islamic Azad University, Babol-Branch, Babol 8415683111, Iran. nnabavi@yahoo.com.
Abdolmajid FataDepartment of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad 9177899191, Iran. stefano.dallacqua@unipd.it.ORCID 0000-0001-8264-6953
Filippo MaggiSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy. filippo.maggi@unicam.it.ORCID 0000-0003-1375-4744
Riccardo PetrelliSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy. riccardo.petrelli@unicam.it.ORCID 0000-0002-4760-1204
Stefano Dall'AcquaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35121 Padova, Italy. Fataa@mums.ac.ir.ORCID 0000-0002-5175-529X
Giovanni BenelliDepartment of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa, Italy. giovanni.benelli@unipi.it.ORCID 0000-0001-8971-6010
Stefania SutDepartment of Agronomy, Food, Natural Resources, Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro, Italy. stefania.sut@unipd.it.
Islamic Azad University, BabolMashhad University of Medical Sciences · IRUniversità di Camerino · ITUniversity of Padua · ITAmol University of Special Modern Technologies · IRBabol University of Medical Sciences · IRUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the most important causative agents of visceral leishmaniasis (VL) is

results24 h MTT assay showed promising antileishmanial activity of thymol and carvacrol, with IC

conclusionsOverall, thymol and carvacrol are highly promising candidates for the development of effective and safe drugs in the fight against VL.

Indexed as

Acyclic MonoterpenesAnimalsCricetinaeCymenesDisease Models, AnimalInhibitory Concentration 50Leishmania infantumLeishmaniasis, VisceralLiverMaleMonoterpenesParasitic Sensitivity TestsThymolTrypanocidal AgentsAcyclic MonoterpenescarvacrolCymeneslinaloolMonoterpenesThymolTrypanocidal Agentsinsect vectorsneglected tropical diseasesprotozoan parasitessandfliesvisceral leishmaniasis

Identifiers

PMID31151304
PMCPMC6600403
OpenAlexW2946022883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.