ArticleMicromachines2019
A Low-Cost, Rapidly Integrated Debubbler (RID) Module for Microfluidic Cell Culture Applications.
Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Modular Integration of Impedance Sensing for Real-Time Assessment of Barrier Integrity.bioRxiv : the preprint server for biology · 2026Article
- Development of a Microfluidics-Based Approach for Investigating Microtubule Polymer Mechanics.Journal of visualized experiments : JoVE · 2025Article
- Microengineering 3D Collagen Matrices with Tumor-Mimetic Gradients in Fiber Alignment.Advanced functional materials · 2024Article
- Transforming Static Barrier Tissue Models into Dynamic Microphysiological Systems.Journal of visualized experiments : JoVE · 2024Article
- Gas transport mechanisms through gas-permeable membranes in microfluidics: A perspective.Biomicrofluidics · 2023Article
- Electropatterning-Contemporary developments for selective particle arrangements employing electrokinetics.Electrophoresis · 2023Review
- Review
- A Scalable, Modular Degasser for Passive In-Line Removal of Bubbles from Biomicrofluidic Devices.Micromachines · 2023Article
- Role of Polymers in Microfluidic Devices.Polymers · 2022Review
- The Modular µSiM Reconfigured: Integration of Microfluidic Capabilities to Study In Vitro Barrier Tissue Models under Flow.Advanced healthcare materials · 2022Article
- Microengineering 3D Collagen Hydrogels with Long-Range Fiber Alignment.Journal of visualized experiments : JoVE · 2022Article
- Modular Microfluidics: Current Status and Future Prospects.Micromachines · 2022Review
- A miniaturized 3D printed pressure regulator (µPR) for microfluidic cell culture applications.Scientific reports · 2022Article
- Perfusion in Organ-on-Chip Models and Its Applicability to the Replication of Spermatogenesis In Vitro.International journal of molecular sciences · 2022Review
- Emergence of debubblers in microfluidics: A critical review.Biomicrofluidics · 2022Review
- Microengineered 3D Collagen Gels with Independently Tunable Fiber Anisotropy and Directionality.Advanced materials technologies · 2021Article
- Fabrication and Applications of Microfluidic Devices: A Review.International journal of molecular sciences · 2021Review
- Microfluidic Devices for Biomedical Applications: Biomedical Microfluidic Devices 2019.Micromachines · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microfluidic platforms use controlled fluid flows to provide physiologically relevant biochemical and biophysical cues to cultured cells in a well-defined and reproducible manner. Undisturbed flows are critical in these systems, and air bubbles entering microfluidic channels can lead to device delamination or cell damage. To prevent bubble entry into microfluidic channels, we report a low-cost, Rapidly Integrated Debubbler (RID) module that is simple to fabricate, inexpensive, and easily combined with existing experimental systems. We demonstrate successful removal of air bubbles spanning three orders of magnitude with a maximum removal rate (dV/dt)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.