Evidence map›Paper›PMID 31151139›Full record

ArticleInternational journal of molecular sciences2019

Role of NF-kB RelB in Aryl Hydrocarbon Receptor-Mediated Ligand Specific Effects.

Yasuhiro Ishihara, Sarah Y Kado, Christiane Hoeper, Shelly Harel, Christoph F A Vogel

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Mechanisms underlying aryl hydrocarbon receptor-driven divergent macrophage function.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
  9. Review
  10. Article
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  13. Article
  14. AhR and Wnt/β-Catenin Signaling Pathways and Their Interplay.Current issues in molecular biology · 2023
    Review
  15. Article
  16. Review
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  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yasuhiro IshiharaCenter for Health and the Environment, University of California, One Shields Avenue, Davis, CA 95616, USA. yaishihara@ucdavis.edu.ORCID 0000-0001-9751-7660
Sarah Y KadoCenter for Health and the Environment, University of California, One Shields Avenue, Davis, CA 95616, USA. sykado@ucdavis.edu.
Christiane HoeperCenter for Health and the Environment, University of California, One Shields Avenue, Davis, CA 95616, USA. choeper@ucdavis.edu.
Shelly HarelCenter for Health and the Environment, University of California, One Shields Avenue, Davis, CA 95616, USA. sharel@ucdavis.edu.
Christoph F A VogelCenter for Health and the Environment, University of California, One Shields Avenue, Davis, CA 95616, USA. cfvogel@ucdavis.edu.
University of California, Davis · USHiroshima University · JP

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
Air pollution, atherosclerosis, and the role of the aryl hydrocarbon receptorR01ES029126 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI VOGEL, CHRISTOPH F A · 2019 to 2023
$1.8M
The protective role of the AhR Repressor in breast cancer developmentR21ES030419 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI VOGEL, CHRISTOPH F A · 2019 to 2020
$432k
NCI NIH HHS P30 CA093373NIEHS NIH HHS R01 ES029126NIEHS NIH HHS R21 ES030419
6 · The paper itself

Abstract

Here, we investigate the role of RelB in the regulation of genes which were identified to be induced in an aryl hydrocarbon receptor (AhR)-dependent manner and critically involved in regulation of immune responses. We analyzed the expression of genes of the AhR gene battery, cytokines, and immune regulatory enzymes in bone marrow-derived macrophages (BMM) and thymus of B6 wildtype (wt) mice and RelB knockout (RelB

Indexed as

AnimalsCytokinesGene ExpressionGene Expression RegulationImmunomodulationLigandsMacrophagesMaleMiceMice, KnockoutProtein BindingReceptors, Aryl HydrocarbonThymus GlandTranscription Factor RelBCytokinesLigandsReceptors, Aryl HydrocarbonRelb protein, mouseTranscription Factor RelBAhRcytokinesDCIDONF-κB RelBTCDD

Identifiers

PMID31151139
PMCPMC6600526
OpenAlexW2947725468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.