ArticleThe Journal of steroid biochemistry and molecular biology2019
The molecular determinants of neurosteroid binding in the GABA(A) receptor.
Article in The Journal of steroid biochemistry and molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Direct measurements of neurosteroid binding to specific sites on GABABritish journal of pharmacology · 2024Article
- Inhibitory Actions of Potentiating Neuroactive Steroids in the Human α1β3γ2L γ-Aminobutyric Acid Type A Receptor.Molecular pharmacology · 2024Article
- Neurosteroid Binding and Actions on GABAJuntendo Iji zasshi = Juntendo medical journal · 2024Review
- Structural insights into opposing actions of neurosteroids on GABANature communications · 2023Article
- Article
- Allosteric modulation of α1β3γ2 GABABiophysical journal · 2023Article
- The Mechanism of Enantioselective Neurosteroid Actions on GABABiomolecules · 2023Article
- Alcohol and Ganaxolone Suppress Tremor via Extra-Synaptic GABATremor and other hyperkinetic movements (New York, N.Y.) · 2023Article
- Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites.eLife · 2022Article
- Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels.Frontiers in molecular biosciences · 2022Article
- Neurosteroid Modulation of GABACurrent neuropharmacology · 2022Article
- Interfacial binding sites for cholesterol on GABABiophysical journal · 2021Article
- Intrasubunit and Intersubunit Steroid Binding Sites Independently and Additively MediateMolecular pharmacology · 2021Article
- Druggable Lipid Binding Sites in Pentameric Ligand-Gated Ion Channels and Transient Receptor Potential Channels.Frontiers in physiology · 2021Review
- Site-specific effects of neurosteroids on GABAeLife · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Neurosteroids positively modulate GABA-A receptor (GABA
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.